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• W2034645900 endingPage "187" @default.
• W2034645900 startingPage "180" @default.
• W2034645900 abstract "In this study, we present, for the first time, human leukocyte antigen (HLA) class I allele and haplotype frequencies at the DNA level in a sample of 142 donors from Turkey. HLA typing was performed by medium-to-high resolution polymerase chain reaction sequence-specific oligonucleotide probes method. The most frequent HLA alleles at class I locus were A*0201(0.257), -B*35(0.204) and -Cw*04(0.173). A*0201-B*35-Cw*04(0.056) was the most common three-locus haplotype. Allele and haplotype frequency comparisons and neighbour-joining dendrograms, constructed using DA genetic distances and correspondence analysis using HLA-A, -B and -C, and -DRB1 allele frequencies, revealed similarities with other Mediterranean and European populations, but not with Mongol populations. These results agree with previous studies and confirm that the present day Turkish population is genetically more similar to its geographic neighbours than its historical neighbours in central Asia. The comprehensive HLA data on the Turkish population at the DNA level including up to six-locus putative haplotypes generated in this study will be useful for further studies." @default.
• W2034645900 created "2016-06-24" @default.
• W2034645900 creator A5049773690 @default.
• W2034645900 creator A5064857776 @default.
• W2034645900 creator A5081836774 @default.
• W2034645900 date "2004-05-06" @default.
• W2034645900 modified "2023-10-10" @default.
• W2034645900 title "Human leukocyte antigen-A, -B and -C alleles and human leukocyte antigen haplotypes in Turkey: relationship to other populations" @default.
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• W2034645900 doi "https://doi.org/10.1111/j.1399-0039.2004.00258.x" @default.
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• W2034645900 hasPublicationYear "2004" @default.
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