Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034646315> ?p ?o ?g. }
- W2034646315 abstract "Experiments have been conducted to examine the impact of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on growth-related signaling in vascular smooth muscle cells (SMCs). A 40% reduction of peak DNA synthesis was observed in SMCs only when TCDD was added during the G0/G1 transition of the cell cycle. Enhanced phosphorylation of several endogenous proteins during this period was coincident with increased tyrosine kinase activity as early as 15 min following TCDD challenge. No changes in protein phosphorylation status occurred in cells treated with TCDD during the G1/S transition or during S phase. Cotreatment of quiescent SMCs with 10 nM TCDD and serum for 3 h reduced serum-inducible binding activity to a 12-O-tetradecanoyl phorbol 13-acetate responsive element (TRE) by approximately 40%. No alterations of constitutive TRE binding were observed in quiescent SMCs treated with TCDD for up to 5 h. These data show that mitogen-related signaling in vascular SMCs is modulated by TCDD selectively during the G0/G1 transition, and these effects influence the growth behavior of these cells." @default.
- W2034646315 created "2016-06-24" @default.
- W2034646315 creator A5019568866 @default.
- W2034646315 creator A5036019764 @default.
- W2034646315 creator A5040329544 @default.
- W2034646315 creator A5052485917 @default.
- W2034646315 date "1997-07-01" @default.
- W2034646315 modified "2023-09-28" @default.
- W2034646315 title "GROWTH-RELATED SIGNALING IN VASCULAR SMOOTH MUSCLE CELLS OS DEREGULATED BY TCDD DURING THE G0/G1, TRANSITION" @default.
- W2034646315 cites W1490083974 @default.
- W2034646315 cites W1562045310 @default.
- W2034646315 cites W1577702300 @default.
- W2034646315 cites W1811606715 @default.
- W2034646315 cites W1838929416 @default.
- W2034646315 cites W1843131799 @default.
- W2034646315 cites W1871934956 @default.
- W2034646315 cites W1935728713 @default.
- W2034646315 cites W1961919679 @default.
- W2034646315 cites W1965535129 @default.
- W2034646315 cites W1966181655 @default.
- W2034646315 cites W1967004332 @default.
- W2034646315 cites W1971556916 @default.
- W2034646315 cites W1974391793 @default.
- W2034646315 cites W1980441590 @default.
- W2034646315 cites W1989210377 @default.
- W2034646315 cites W1993356518 @default.
- W2034646315 cites W1999086913 @default.
- W2034646315 cites W2001609760 @default.
- W2034646315 cites W2004670577 @default.
- W2034646315 cites W2008143318 @default.
- W2034646315 cites W2022643576 @default.
- W2034646315 cites W2022898466 @default.
- W2034646315 cites W2024170705 @default.
- W2034646315 cites W2024971989 @default.
- W2034646315 cites W2027229755 @default.
- W2034646315 cites W2035063099 @default.
- W2034646315 cites W2038092360 @default.
- W2034646315 cites W2040816657 @default.
- W2034646315 cites W2041678451 @default.
- W2034646315 cites W2044980718 @default.
- W2034646315 cites W2046435651 @default.
- W2034646315 cites W2055006638 @default.
- W2034646315 cites W2059655527 @default.
- W2034646315 cites W2060052408 @default.
- W2034646315 cites W2065904520 @default.
- W2034646315 cites W2068055791 @default.
- W2034646315 cites W2075002147 @default.
- W2034646315 cites W2076842495 @default.
- W2034646315 cites W2080960719 @default.
- W2034646315 cites W2087269733 @default.
- W2034646315 cites W2087717745 @default.
- W2034646315 cites W2094872845 @default.
- W2034646315 cites W2095522527 @default.
- W2034646315 cites W2107359522 @default.
- W2034646315 cites W2131113110 @default.
- W2034646315 cites W2168476632 @default.
- W2034646315 cites W2177359510 @default.
- W2034646315 cites W2394700190 @default.
- W2034646315 cites W2476209145 @default.
- W2034646315 cites W2495143481 @default.
- W2034646315 doi "https://doi.org/10.1080/00984109708984031" @default.
- W2034646315 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9202717" @default.
- W2034646315 hasPublicationYear "1997" @default.
- W2034646315 type Work @default.
- W2034646315 sameAs 2034646315 @default.
- W2034646315 citedByCount "3" @default.
- W2034646315 crossrefType "journal-article" @default.
- W2034646315 hasAuthorship W2034646315A5019568866 @default.
- W2034646315 hasAuthorship W2034646315A5036019764 @default.
- W2034646315 hasAuthorship W2034646315A5040329544 @default.
- W2034646315 hasAuthorship W2034646315A5052485917 @default.
- W2034646315 hasConcept C104317684 @default.
- W2034646315 hasConcept C11960822 @default.
- W2034646315 hasConcept C126322002 @default.
- W2034646315 hasConcept C134018914 @default.
- W2034646315 hasConcept C1491633281 @default.
- W2034646315 hasConcept C16613235 @default.
- W2034646315 hasConcept C185592680 @default.
- W2034646315 hasConcept C194232998 @default.
- W2034646315 hasConcept C195794163 @default.
- W2034646315 hasConcept C2779395532 @default.
- W2034646315 hasConcept C2780043322 @default.
- W2034646315 hasConcept C29537977 @default.
- W2034646315 hasConcept C2992686903 @default.
- W2034646315 hasConcept C552990157 @default.
- W2034646315 hasConcept C55493867 @default.
- W2034646315 hasConcept C62112901 @default.
- W2034646315 hasConcept C62478195 @default.
- W2034646315 hasConcept C64241487 @default.
- W2034646315 hasConcept C71924100 @default.
- W2034646315 hasConcept C86803240 @default.
- W2034646315 hasConcept C95444343 @default.
- W2034646315 hasConceptScore W2034646315C104317684 @default.
- W2034646315 hasConceptScore W2034646315C11960822 @default.
- W2034646315 hasConceptScore W2034646315C126322002 @default.
- W2034646315 hasConceptScore W2034646315C134018914 @default.
- W2034646315 hasConceptScore W2034646315C1491633281 @default.
- W2034646315 hasConceptScore W2034646315C16613235 @default.
- W2034646315 hasConceptScore W2034646315C185592680 @default.
- W2034646315 hasConceptScore W2034646315C194232998 @default.