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• W2034646795 abstract "An efficient synthesis of compound 1 featuring a novel sequential Friedel–Crafts alkylation strategy to construct the 4-aryl-tetrahydroisoquinoline core structure has been developed. Resolution with (d/l)-di-p-toluoyl-tartaric acid is utilized to provide the enantiomerically pure material. Overall, the route is concise and amenable for large-scale synthesis." @default.
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• W2034646795 date "2007-11-01" @default.
• W2034646795 modified "2023-10-14" @default.
• W2034646795 title "A Practical Synthesis of Enantiopure 7-Alkoxy-4-aryl-tetrahydroisoquinoline, a Dual Serotonin Reuptake Inhibitor/Histamine H₃ Antagonist" @default.
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• W2034646795 doi "https://doi.org/10.1021/op700183q" @default.
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