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- W2034647716 abstract "SURVIVAL beyond adolescence is unusual in chronic granulomatous disease of childhood because of a marked susceptibility to serious bacterial and fungal infection. 1 Therefore, diagnosis of this disease in patients older than 18 years of age is rarely reported. 2,3 Recently, we have diagnosed chronic granulomatous disease in a 27-year-old man suffering from atypical mycobacterial pneumonitis and osteomyelitis. Report of a Case A 27-year-old man was referred to the National Institutes of Health (NIH). He had had pneumonitis for two months, and his past history included a staphylococcal thigh abscess and several bouts of facial cellulitis. The patient's 12-year-old sister was known to have chronic granulomatous disease complicated by chronic Nocardia osteomyelitis, and a brother had died of disseminated tuberculosis at 1 year of age. Two months prior to referral, pleuritic chest pain developed with fever, night sweats, chills, and a 13.5-kg (30-lb) weight loss. A chest x-ray film showed" @default.
- W2034647716 created "2016-06-24" @default.
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- W2034647716 date "1975-09-22" @default.
- W2034647716 modified "2023-10-18" @default.
- W2034647716 title "Chronic granulomatous disease. Diagnosis in a 27-year-old man with Mycobacterium fortuitum" @default.
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- W2034647716 doi "https://doi.org/10.1001/jama.233.12.1295" @default.
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