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• W2034650105 startingPage "422" @default.
• W2034650105 abstract "Giant cell arteritis (GCA) is closely identified with the temporal arteritis-polymyalgiarheumatica syndrome of the elderly. It is also a systemic disease that can cripple and kill. Up to 15% of patients with temporal arteritis may have angiographic evidence of extracranial GCA, and aortic insufficiency, ruptured aortic aneurysm, aortic dissection, stroke, or myocardial infarction may be the initial manifestation of systemic GCA. A review of 72 cases of aortic and extracranial GCA, all with histopathologic verification of the disease, revealed that 25% of patients with aortic and extracranial large-vessel GCA had asymptomatic temporal arteritis; the ascending aorta and aortic arch were most frequently involved (39%), followed by the subclavian and axillary arteries (26%), and the femoropopliteal arteries (18%). Nine patients (12.5%) underwent an upper or lower limb amputation. Of the 18 patients whose death was directly attributable to extracranial GCA the causes were ruptured aortic aneurysm (6), aortic dissection (6), stroke (3), and myocardial infarction (3). The findings of these 72 cases caution against attributing all aortic and large-vessel arterial disease in the elderly to atherosclerosis and emphasize that timely surgical intervention may be necessary for life-saving and limb-salvage in patients with aortic and extracranial GCA." @default.
• W2034650105 created "2016-06-24" @default.
• W2034650105 creator A5091598760 @default.
• W2034650105 date "1995-06-01" @default.
• W2034650105 modified "2023-10-18" @default.
• W2034650105 title "Aortic and extracranial large vessel giant cell arteritis: A review of 72 cases with histopathologic documentation" @default.
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• W2034650105 doi "https://doi.org/10.1016/s0049-0172(95)80010-7" @default.
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• W2034650105 hasPublicationYear "1995" @default.
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