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• W2034651750 abstract "No AccessJournal of UrologyAdult urology1 Jan 2007Does Body Mass Index Affect Preoperative Prostate Specific Antigen Velocity or Pathological Outcomes After Radical Prostatectomy? Stacy Loeb, Xiaoying Yu, Robert B. Nadler, Kimberly A. Roehl, Misop Han, Sheila A. Hawkins, and William J. Catalona Stacy LoebStacy Loeb Department of Urology, Georgetown University School of Medicine, Washington, D. C. More articles by this author , Xiaoying YuXiaoying Yu Department of Urology, Northwestern Feinberg School of Medicine, Chicago, Illinois More articles by this author , Robert B. NadlerRobert B. Nadler Department of Urology, Northwestern Feinberg School of Medicine, Chicago, Illinois More articles by this author , Kimberly A. RoehlKimberly A. Roehl Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri More articles by this author , Misop HanMisop Han Department of Urology, Northwestern Feinberg School of Medicine, Chicago, Illinois More articles by this author , Sheila A. HawkinsSheila A. Hawkins Department of Urology, Northwestern Feinberg School of Medicine, Chicago, Illinois More articles by this author , and William J. CatalonaWilliam J. Catalona Department of Urology, Northwestern Feinberg School of Medicine, Chicago, Illinois Department of Surgery/Urology, Washington University School of Medicine, St. Louis, Missouri Financial interest and/or other relationship with Beckman Coulter. More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2006.08.097AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: Several studies suggest that obesity may be associated with more aggressive prostate cancer. Similarly the rate of serum prostate specific antigen change is associated with adverse tumor features and prostate cancer specific mortality rates after radical prostatectomy and radiation therapy. We examined the associations among obesity, prostate specific antigen velocity and adverse tumor features in men treated with radical prostatectomy. Materials and Methods: A total of 587 men with documented preoperative height and weight measurements underwent radical prostatectomy. Prostate specific antigen velocity and other clinicopathological features were compared among men with a body mass index of less than 25, 25 to 29.9 and 30 or greater. Results: Although Gleason score and prostate volume were similar among groups, there was a significantly lower proportion with organ confined disease and fewer low volume tumors as body mass index increased. Of patients with a body mass index of 30 or greater 52% had a preoperative prostate specific antigen velocity of more than 2 ng/ml yearly compared to 34% with a body mass index of 25 to 29.9 and 26% with a body mass index of less than 25 (p = 0.04). Although on univariate analysis body mass index was associated with adverse clinical and pathological tumor features, on multivariate analysis with other preoperative variables body mass index did not add significant independent predictive information concerning pathological stage (OR 1.02, 95% CI 0.96–1.08). Conclusions: Obesity was significantly associated with several adverse pathological features. However, it did not provide independent predictive information concerning final pathological tumor stage. Nevertheless, obesity was significantly associated with increased preoperative prostate specific antigen velocity. Additional studies are needed to further clarify the links between body mass index, prostate specific antigen velocity and prostate cancer progression, and determine whether weight reduction could lead to improved outcomes. References 1 : Prevalence and trends in obesity among US adults, 1999–2000. JAMA2002; 288: 1723. Google Scholar 2 : Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults. N Engl J Med2003; 348: 1625. Google Scholar 3 : Body size and prostate cancer: a 20-year follow-up study among 135006 Swedish construction workers. J Natl Cancer Inst1997; 89: 385. Google Scholar 4 : Obesity and biochemical outcome following radical prostatectomy for organ confined disease with negative surgical margins. J Urol2004; 172: 520. Link, Google Scholar 5 : Stronger association between obesity and biochemical progression after radical prostatectomy among men treated in the last 10 years. Clin Cancer Res2005; 11: 2883. Google Scholar 6 : Body mass index is weakly associated with, and not a helpful predictor of, disease progression in men with clinically localized prostate carcinoma treated with radical prostatectomy. Cancer2005; 103: 2030. Google Scholar 7 : Preoperative PSA velocity and the risk of death from prostate cancer after radical prostatectomy. N Engl J Med2004; 351: 125. Google Scholar 8 Physical status: the use and interpretation of anthropometry: Report of a WHO Expert Committee. World Health Organ Tech Rep Ser1995; 854: 1. Google Scholar 9 : Comparison of different methods for calculating PSA velocity: importance of time interval prior to diagnosis of prostate cancer. J Urol2005; 173: 128. Link, Google Scholar 10 : Percentage carcinoma as a measure of prostatic tumor size in radical prostatectomy tissues. Mod Pathol1997; 10: 326. Google Scholar 11 Cancer Facts and Figures. American Cancer Society. Available at: http://www.cancer.org/docroot/MED/content/downloads/MED_1_1x_CFF2005_Estimated_New_Cases_Deaths_by_Sex_US.asp,2005. Accessed September 5, 2005. Google Scholar 12 : Family history of prostate cancer and obesity in relation to high-grade disease and extraprostatic extension in young men with prostate cancer. Prostate2003; 55: 140. Google Scholar 13 : Obesity and risk of biochemical progression following radical prostatectomy at a tertiary care referral center. J Urol2005; 174: 919. Link, Google Scholar 14 : Impact of obesity on prostate cancer recurrence after radical prostatectomy: data from CaPSURE. Urology2005; 66: 1060. Google Scholar 15 : Leptin and prostate cancer. Prostate2001; 46: 62. Google Scholar 16 : Obesity, weight gain, and risk of biochemical failure among prostate cancer patients following prostatectomy. Clin Cancer Res2005; 11: 6889. Google Scholar 17 : Pathologic variables and recurrence rates as related to obesity and race in men with prostate cancer undergoing radical prostatectomy. J Clin Oncol2004; 22: 439. Google Scholar © 2007 by American Urological AssociationFiguresReferencesRelatedDetailsCited ByPruthi R, Swords K, Schultz H, Carson C and Wallen E (2018) The Impact of Obesity on the Diagnosis of Prostate Cancer Using a Modern Extended Biopsy SchemeJournal of Urology, VOL. 181, NO. 2, (574-578), Online publication date: 1-Feb-2009.Gonzalgo M (2018) Editorial CommentJournal of Urology, VOL. 179, NO. 3, (890-891), Online publication date: 1-Mar-2008. Volume 177Issue 1January 2007Page: 102-106 Advertisement Copyright & Permissions© 2007 by American Urological AssociationKeywordsprostateprostatectomyprostatic neoplasmsobesityMetricsAuthor Information Stacy Loeb Department of Urology, Georgetown University School of Medicine, Washington, D. C. More articles by this author Xiaoying Yu Department of Urology, Northwestern Feinberg School of Medicine, Chicago, Illinois More articles by this author Robert B. Nadler Department of Urology, Northwestern Feinberg School of Medicine, Chicago, Illinois More articles by this author Kimberly A. Roehl Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri More articles by this author Misop Han Department of Urology, Northwestern Feinberg School of Medicine, Chicago, Illinois More articles by this author Sheila A. Hawkins Department of Urology, Northwestern Feinberg School of Medicine, Chicago, Illinois More articles by this author William J. Catalona Department of Urology, Northwestern Feinberg School of Medicine, Chicago, Illinois Department of Surgery/Urology, Washington University School of Medicine, St. Louis, Missouri Financial interest and/or other relationship with Beckman Coulter. More articles by this author Expand All Advertisement PDF DownloadLoading ..." @default.
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