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- W2034653152 abstract "In Reply.— I fully agree with Dr Daves that in some people the colon responds to stress. Indeed, as I stated, functional abdominal pain is often stress related. This pain may well be the result of spasm, although additional mechanisms such as heightened sensitivity to colonic distention could play a role. In any case, there is very little evidence that colonic spasm leads to diverticular disease. Intraluminal pressure 1 and motility 2 are usually normal in patients with diverticular disease. Other factors such as intrinsic abnormalities of colonic musculature, weakness of the colonic wall, and diet may be of greater importance in the development of diverticula. 3 The literature does not support Dr Daves' clinical impression that abdominal pain (left lower quadrant or otherwise) is especially associated with uncomplicated diverticular disease. A study referenced in my answer found that abdominal pain was no more common in patients with diverticula on" @default.
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- W2034653152 date "1986-06-27" @default.
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- W2034653152 title "Stress, the Colon, and Diverticulosis-Reply" @default.
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- W2034653152 doi "https://doi.org/10.1001/jama.1986.03370240036027" @default.
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