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- W2034659801 abstract "Purpose: To determine a role for the mammalian target of rapamycin (mTOR) in urokinase (uPA)-induced smooth muscle cell (SMC) migration, and to examine specific kinase pathways that may act downstream of mTOR to influence the response of SMCs to uPA. Background: Vascular SMC migration is an important component of the development of intimal hyperplasia. During tissue remodeling, uPA is one of the key serine proteases involved and stimulates SMC migration in vitro. Rapamycin is an antifungal and immunosuppressant that inhibits mTOR, which regulates p70S6 kinase (p70S6K) activity." @default.
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- W2034659801 date "2006-02-01" @default.
- W2034659801 modified "2023-09-26" @default.
- W2034659801 title "Urokinase-induced smooth muscle cell migration involves the mammalian target of rapamycin" @default.
- W2034659801 doi "https://doi.org/10.1016/j.jss.2005.11.203" @default.
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