Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034662738> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2034662738 endingPage "836" @default.
- W2034662738 startingPage "834" @default.
- W2034662738 abstract "Funding sources: none. Conflicts of interest: none declared. Dear Editor, Ustekinumab is a human monoclonal antibody, which binds to and inhibits interleukin (IL)‐12p40, and is used to treat moderate‐to‐severe psoriasis and psoriatic arthritis. Sarcoidosis is a systemic granulomatous disease in which IL‐12 levels are elevated in tissues, serum and bronchoalveolar lavage samples of affected patients.1 Therefore, there is a rationale for the use of ustekinumab in treating sarcoidosis. The paradoxical induction of a wide range of autoimmune processes such as lupus erythematosus, vasculitis, sarcoidosis and psoriasis, developing after the initiation of antitumour necrosis factor (anti‐TNF) biological therapies, is increasingly being reported.2 We present the first reported case, to our knowledge, of sarcoidosis developing in a patient receiving ustekinumab for chronic plaque psoriasis (or indeed any indication). A 42‐year‐old white female patient with psoriatic arthritis and severe, difficult‐to‐control, chronic plaque psoriasis [Psoriasis Area and Severity Index (PASI) 19·3 and Dermatology Life Quality Index (DLQI) 26 at initiation of therapy] had been treated with ustekinumab 45 mg subcutaneously for 14 months when she presented with lethargy, weight loss, night sweats, a dry cough, dyspnoea and painful lesions on the lower legs. Previous treatments included phototherapy, ciclosporin, acitretin, adalimumab and infliximab (both biologics in combination with methotrexate). Methotrexate 20 mg weekly was continued while ustekinumab was initiated." @default.
- W2034662738 created "2016-06-24" @default.
- W2034662738 creator A5008567640 @default.
- W2034662738 creator A5010749476 @default.
- W2034662738 creator A5026606145 @default.
- W2034662738 creator A5029579914 @default.
- W2034662738 creator A5047643527 @default.
- W2034662738 creator A5055501731 @default.
- W2034662738 creator A5058286878 @default.
- W2034662738 creator A5071573183 @default.
- W2034662738 date "2015-01-28" @default.
- W2034662738 modified "2023-09-27" @default.
- W2034662738 title "Acute systemic sarcoidosis complicating ustekinumab therapy for chronic plaque psoriasis" @default.
- W2034662738 cites W1661616496 @default.
- W2034662738 cites W2012285680 @default.
- W2034662738 cites W2062612389 @default.
- W2034662738 cites W2082834134 @default.
- W2034662738 cites W2177368405 @default.
- W2034662738 doi "https://doi.org/10.1111/bjd.13365" @default.
- W2034662738 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25141774" @default.
- W2034662738 hasPublicationYear "2015" @default.
- W2034662738 type Work @default.
- W2034662738 sameAs 2034662738 @default.
- W2034662738 citedByCount "16" @default.
- W2034662738 countsByYear W20346627382015 @default.
- W2034662738 countsByYear W20346627382017 @default.
- W2034662738 countsByYear W20346627382018 @default.
- W2034662738 countsByYear W20346627382019 @default.
- W2034662738 countsByYear W20346627382020 @default.
- W2034662738 countsByYear W20346627382021 @default.
- W2034662738 countsByYear W20346627382022 @default.
- W2034662738 countsByYear W20346627382023 @default.
- W2034662738 crossrefType "journal-article" @default.
- W2034662738 hasAuthorship W2034662738A5008567640 @default.
- W2034662738 hasAuthorship W2034662738A5010749476 @default.
- W2034662738 hasAuthorship W2034662738A5026606145 @default.
- W2034662738 hasAuthorship W2034662738A5029579914 @default.
- W2034662738 hasAuthorship W2034662738A5047643527 @default.
- W2034662738 hasAuthorship W2034662738A5055501731 @default.
- W2034662738 hasAuthorship W2034662738A5058286878 @default.
- W2034662738 hasAuthorship W2034662738A5071573183 @default.
- W2034662738 hasConcept C126322002 @default.
- W2034662738 hasConcept C16005928 @default.
- W2034662738 hasConcept C17991360 @default.
- W2034662738 hasConcept C203014093 @default.
- W2034662738 hasConcept C2776260265 @default.
- W2034662738 hasConcept C2777011040 @default.
- W2034662738 hasConcept C2777138892 @default.
- W2034662738 hasConcept C2777226972 @default.
- W2034662738 hasConcept C2777575956 @default.
- W2034662738 hasConcept C2778496887 @default.
- W2034662738 hasConcept C2778975655 @default.
- W2034662738 hasConcept C2780132546 @default.
- W2034662738 hasConcept C2780564577 @default.
- W2034662738 hasConcept C2781301800 @default.
- W2034662738 hasConcept C71924100 @default.
- W2034662738 hasConceptScore W2034662738C126322002 @default.
- W2034662738 hasConceptScore W2034662738C16005928 @default.
- W2034662738 hasConceptScore W2034662738C17991360 @default.
- W2034662738 hasConceptScore W2034662738C203014093 @default.
- W2034662738 hasConceptScore W2034662738C2776260265 @default.
- W2034662738 hasConceptScore W2034662738C2777011040 @default.
- W2034662738 hasConceptScore W2034662738C2777138892 @default.
- W2034662738 hasConceptScore W2034662738C2777226972 @default.
- W2034662738 hasConceptScore W2034662738C2777575956 @default.
- W2034662738 hasConceptScore W2034662738C2778496887 @default.
- W2034662738 hasConceptScore W2034662738C2778975655 @default.
- W2034662738 hasConceptScore W2034662738C2780132546 @default.
- W2034662738 hasConceptScore W2034662738C2780564577 @default.
- W2034662738 hasConceptScore W2034662738C2781301800 @default.
- W2034662738 hasConceptScore W2034662738C71924100 @default.
- W2034662738 hasIssue "3" @default.
- W2034662738 hasLocation W20346627381 @default.
- W2034662738 hasLocation W20346627382 @default.
- W2034662738 hasOpenAccess W2034662738 @default.
- W2034662738 hasPrimaryLocation W20346627381 @default.
- W2034662738 hasRelatedWork W1485937383 @default.
- W2034662738 hasRelatedWork W1920699911 @default.
- W2034662738 hasRelatedWork W1958224858 @default.
- W2034662738 hasRelatedWork W1970925217 @default.
- W2034662738 hasRelatedWork W2001428968 @default.
- W2034662738 hasRelatedWork W2062801585 @default.
- W2034662738 hasRelatedWork W2184813578 @default.
- W2034662738 hasRelatedWork W2235471063 @default.
- W2034662738 hasRelatedWork W2564603710 @default.
- W2034662738 hasRelatedWork W6525474 @default.
- W2034662738 hasVolume "172" @default.
- W2034662738 isParatext "false" @default.
- W2034662738 isRetracted "false" @default.
- W2034662738 magId "2034662738" @default.
- W2034662738 workType "article" @default.