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- W2034663400 abstract "We have developed a low power neurotransmitter biosensor which can be applied in an implantable closed-loop CMOS neurotrophic factor delivery microsystem which by protecting the healthy neurons and restoring damaged ones can maintain therapeutic levels of chemical concentrations in the brain. The hybrid microsystem is composed of novel biosensor that can sense micromolar concentration of neurotransmitters (dopamine) and embedded negative feedback circuits that control the flow of pharmacological agents in micro fluidic channels. The focus of this manuscript is on sensing, control and decision making circuitry. It consists of a current conveyer, a low noise low power amplifier, an integrator and a comparator with offset cancelation. Circuit is fabricated in CMOS 0.18 um with low power consumption of 921 nW." @default.
- W2034663400 created "2016-06-24" @default.
- W2034663400 creator A5039034962 @default.
- W2034663400 creator A5063084720 @default.
- W2034663400 date "2014-02-01" @default.
- W2034663400 modified "2023-10-16" @default.
- W2034663400 title "Low power CMOS neurochemical biosensor application in an implantable intelligent neurotrophic factor delivery hybrid microsystem for Parkinson's" @default.
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- W2034663400 doi "https://doi.org/10.1109/mecbme.2014.6783223" @default.
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