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• W2034664096 abstract "A practical cross-coupling of amides with alkynyl bromides using catalytic CuSO(4).5H(2)O and 1,10-phenanthroline is described here. This catalytic protocol is more environmentally friendly than the use of CuCN or copper halides and provides a general entry for syntheses of ynamides including various new sulfonyl and heteroaromatic amine substituted ynamides. Given the interest in ynamides, this N-alkynylation of amides should be significant for the future of ynamides in organic synthesis." @default.
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• W2034664096 date "2004-03-02" @default.
• W2034664096 modified "2023-10-02" @default.
• W2034664096 title "Copper Sulfate-Pentahydrate-1,10-Phenanthroline Catalyzed Amidations of Alkynyl Bromides. Synthesis of Heteroaromatic Amine Substituted Ynamides" @default.
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• W2034664096 doi "https://doi.org/10.1021/ol049827e" @default.
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