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- W2034677002 abstract "Techniques for controlling the rate and duration of drug delivery, while targeting specific locations of the body for treatment, to deliver the cargo (drugs or DNA) to particular parts of the body by what are becoming called smart drug carriers have gained increased attention during recent years. Using such smart carriers, researchers have also been investigating a number of physical energy forces including: magnetic fields, ultrasound, electric fields, temperature gradients, photoactivation or photorelease mechanisms, and mechanical forces to enhance drug delivery within the targeted cells or tissues and also to activate the drugs using a similar or a different type of external trigger. This review aims to cover a number of such physical energy modalities. Various advanced techniques such as magnetoporation, electroporation, iontophoresis, sonoporation/mechnoporation, phonophoresis, optoporation and thermoporation will be covered in the review. Special emphasis will be placed on photodynamic therapy owing to the experience of the authors' laboratory in this area, but other types of drug cargo and DNA vectors will also be covered. Photothermal therapy and theranostics will also be discussed." @default.
- W2034677002 created "2016-06-24" @default.
- W2034677002 creator A5001374433 @default.
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- W2034677002 creator A5023821769 @default.
- W2034677002 creator A5031974923 @default.
- W2034677002 creator A5077577510 @default.
- W2034677002 date "2014-05-01" @default.
- W2034677002 modified "2023-09-30" @default.
- W2034677002 title "Physical energy for drug delivery; poration, concentration and activation" @default.
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