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• W2034679263 startingPage "1593" @default.
• W2034679263 abstract "There have been numerous attempts to describe the mechanism of B-Z transition. Our simulations based on the stochastic difference equation with length algorithm show that a short DNA oligomer will tend to unwind and overstretch during the transition. The overstretching of DNA is then understood from the Zhou, Zhang, and Ou-Yang model. Unlike the Harvey model, the stretched intermediate model does not pose any steric dilemma; we are able to show that the chain sense reversal progresses spontaneously using the stretched intermediate model. A nonlinear DNA model is used to describe the origins and mechanism of base rotation in the stretched intermediate state of DNA. We also propose an experiment that can verify the existence of a stretched intermediate state during B-Z transition, thus opening up fresh grounds for experimentation in this field." @default.
• W2034679263 created "2016-06-24" @default.
• W2034679263 creator A5022750933 @default.
• W2034679263 creator A5069207859 @default.
• W2034679263 date "2005-03-01" @default.
• W2034679263 modified "2023-10-11" @default.
• W2034679263 title "The Stretched Intermediate Model of B-Z DNA Transition" @default.
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• W2034679263 doi "https://doi.org/10.1529/biophysj.104.052027" @default.
• W2034679263 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1305216" @default.
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• W2034679263 hasPublicationYear "2005" @default.
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