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- W2034680712 abstract "Effects of pyridoxal 5′-phosphate on enzymatic reactions of cross-link formation in collagen and elastin were studied. In this study, we observed that pyridoxal 5′-phosphate combined with β-aminopropionitrile to competitively reverse the inhibition of activities of vitamin B6-dependent enzymes brought about by β-aminopropionitrile in vitro. In addition, we observed that a sufficient dose of pyridoxine hydrochloride prevented the occurrence of dissecting aneurysm of SD rats fed β-aminopropionitrile. From the above results, we assume that β-aminopropionitrile inhibited the lysyl oxidase by binding with the pyridoxal 5′-phosphate that is necessary for the activation of lysyl oxidase." @default.
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- W2034680712 date "1987-01-01" @default.
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- W2034680712 title "Effect of Vitamin B6 on Dissecting Aneurysm of Rats Fed β-Aminopropionitrle" @default.
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