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- W2034681231 abstract "Parthenolide (C15H2003), a sesquiterpene lactone, was shown to be the major antimicrobial constituent of crude extracts obtained by dipping leaves or seeds of Chrysanthemum parthenium in chloroform. It was separated in pure form by thin-layer chromatography. Parthenolide was probably present in two-lobed glands on both surfaces of leaves and between ridges on the seeds. Parthenolide inhibited growth of Gram-positive bacteria, yeasts and filamentous fungi in vitro. Gram-negative bacteria were unaffected. A number of the Gram-positive bacteria and yeasts were killed by parthenolide in nutrient broth, though the concentration required varied greatly with the species. Species of Bacillus without endospores were particularly sensitive. Filamentous fungi were relatively insensitive. Parthenolide reduced infection when added to spore-containing droplets of two facultative pathogens on chrysanthemum petals and bean leaves. Parthenolide was not phytotoxic except at very high concentrations but crude extracts from C. parthenium leaves were strongly phytotoxic. The possible role of antimicrobial substances in glands in relation to defence of the plant against disease is discussed." @default.
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- W2034681231 date "1979-09-01" @default.
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- W2034681231 title "Antimicrobial properties and possible rôle in host-pathogen interactions of parthenolide, a sesquiterpene lactone isolated from glands of Chrysanthemum parthenium" @default.
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- W2034681231 doi "https://doi.org/10.1016/0048-4059(79)90067-5" @default.
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