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- W2034682857 abstract "The capping of the 3′-ends of thrombin binding aptamers (TBAs) with bridged nucleotides increased the nuclease resistances and the stabilities in human serum. The binding abilities of the aptamers were not affected by the capping. The capping could be simply executed via a one step enzymatic process using 2′,4′-bridged nucleoside 5′-triphosphate and terminal deoxynucleotidyl transferase." @default.
- W2034682857 created "2016-06-24" @default.
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- W2034682857 date "2010-03-01" @default.
- W2034682857 modified "2023-10-16" @default.
- W2034682857 title "Effect of 3′-end capping of aptamer with various 2′,4′-bridged nucleotides: Enzymatic post-modification toward a practical use of polyclonal aptamers" @default.
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- W2034682857 doi "https://doi.org/10.1016/j.bmcl.2010.01.028" @default.
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