FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034684388> ?p ?o ?g. }

• W2034684388 endingPage "202" @default.
• W2034684388 startingPage "193" @default.
• W2034684388 abstract "Background. The incidence of stroke in adulthood increases with advancing age, but there is little understanding of how poststroke treatment should be tailored by age. Objective. The goal of this study was to determine if age and task specificity of rehabilitative training affect behavioral improvement and motor cortical organization after stroke. Methods. Young and aged mice were trained to proficiency on the Pasta Matrix Reaching Task prior to lesion induction in primary motor cortex with endothelin-1. After a short recovery period, mice received 9 weeks of rehabilitative training on either the previously learned task (Pasta Matrix Reaching), a different reaching task (Tray Reaching), or no training. To determine the extent of relearning, mice were tested once weekly on the Pasta Matrix Reaching Task. Mice then underwent intracortical microstimulation mapping to resolve the remaining forelimb movement representations in perilesion motor cortex. Results. Although aged mice had significantly larger lesions compared with young mice, Pasta Matrix Reaching served as effective rehabilitative training for both age-groups. Young animals also showed improvement after Tray Reaching. Behavioral improvement in young mice was associated with an expansion of the rostral forelimb area (“premotor” cortex), but we failed to see reorganization in the aged brain, despite similar behavioral improvements. Conclusions. Our results indicate that reorganization of motor cortex may be limited by either aging or greater tissue damage, but the capacity to improve motor function via task-specific rehabilitative training continues to be well maintained in aged animals." @default.
• W2034684388 created "2016-06-24" @default.
• W2034684388 creator A5004729460 @default.
• W2034684388 creator A5044537776 @default.
• W2034684388 creator A5044573364 @default.
• W2034684388 creator A5055291900 @default.
• W2034684388 creator A5055617122 @default.
• W2034684388 creator A5074722254 @default.
• W2034684388 creator A5075481727 @default.
• W2034684388 date "2014-07-08" @default.
• W2034684388 modified "2023-10-12" @default.
• W2034684388 title "Age-Dependent Reorganization of Peri-Infarct “Premotor” Cortex With Task-Specific Rehabilitative Training in Mice" @default.
• W2034684388 cites W1781000532 @default.
• W2034684388 cites W1964107498 @default.
• W2034684388 cites W1967094558 @default.
• W2034684388 cites W1971279277 @default.
• W2034684388 cites W1978284348 @default.
• W2034684388 cites W1979226561 @default.
• W2034684388 cites W1979880527 @default.
• W2034684388 cites W1981990510 @default.
• W2034684388 cites W1995992313 @default.
• W2034684388 cites W2012154384 @default.
• W2034684388 cites W2030697228 @default.
• W2034684388 cites W2038514344 @default.
• W2034684388 cites W2055367956 @default.
• W2034684388 cites W2059976173 @default.
• W2034684388 cites W2075358425 @default.
• W2034684388 cites W2078143069 @default.
• W2034684388 cites W2096591841 @default.
• W2034684388 cites W2110575642 @default.
• W2034684388 cites W2113255962 @default.
• W2034684388 cites W2114623260 @default.
• W2034684388 cites W2122358589 @default.
• W2034684388 cites W2139148538 @default.
• W2034684388 cites W2141106841 @default.
• W2034684388 cites W2142875212 @default.
• W2034684388 cites W2147849931 @default.
• W2034684388 cites W2154385999 @default.
• W2034684388 cites W2164870922 @default.
• W2034684388 cites W2334275515 @default.
• W2034684388 cites W4292329040 @default.
• W2034684388 cites W4361867705 @default.
• W2034684388 doi "https://doi.org/10.1177/1545968314541329" @default.
• W2034684388 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4277492" @default.
• W2034684388 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25009222" @default.
• W2034684388 hasPublicationYear "2014" @default.
• W2034684388 type Work @default.
• W2034684388 sameAs 2034684388 @default.
• W2034684388 citedByCount "41" @default.
• W2034684388 countsByYear W20346843882014 @default.
• W2034684388 countsByYear W20346843882015 @default.
• W2034684388 countsByYear W20346843882016 @default.
• W2034684388 countsByYear W20346843882017 @default.
• W2034684388 countsByYear W20346843882018 @default.
• W2034684388 countsByYear W20346843882019 @default.
• W2034684388 countsByYear W20346843882020 @default.
• W2034684388 countsByYear W20346843882021 @default.
• W2034684388 countsByYear W20346843882022 @default.
• W2034684388 countsByYear W20346843882023 @default.
• W2034684388 crossrefType "journal-article" @default.
• W2034684388 hasAuthorship W2034684388A5004729460 @default.
• W2034684388 hasAuthorship W2034684388A5044537776 @default.
• W2034684388 hasAuthorship W2034684388A5044573364 @default.
• W2034684388 hasAuthorship W2034684388A5055291900 @default.
• W2034684388 hasAuthorship W2034684388A5055617122 @default.
• W2034684388 hasAuthorship W2034684388A5074722254 @default.
• W2034684388 hasAuthorship W2034684388A5075481727 @default.
• W2034684388 hasBestOaLocation W20346843882 @default.
• W2034684388 hasConcept C105702510 @default.
• W2034684388 hasConcept C107690735 @default.
• W2034684388 hasConcept C127413603 @default.
• W2034684388 hasConcept C140530291 @default.
• W2034684388 hasConcept C15744967 @default.
• W2034684388 hasConcept C169760540 @default.
• W2034684388 hasConcept C24998067 @default.
• W2034684388 hasConcept C2777348757 @default.
• W2034684388 hasConcept C2778373776 @default.
• W2034684388 hasConcept C2778646069 @default.
• W2034684388 hasConcept C2778818304 @default.
• W2034684388 hasConcept C2779534489 @default.
• W2034684388 hasConcept C2780307956 @default.
• W2034684388 hasConcept C2780645631 @default.
• W2034684388 hasConcept C47177892 @default.
• W2034684388 hasConcept C53927964 @default.
• W2034684388 hasConcept C71924100 @default.
• W2034684388 hasConcept C78519656 @default.
• W2034684388 hasConcept C99508421 @default.
• W2034684388 hasConceptScore W2034684388C105702510 @default.
• W2034684388 hasConceptScore W2034684388C107690735 @default.
• W2034684388 hasConceptScore W2034684388C127413603 @default.
• W2034684388 hasConceptScore W2034684388C140530291 @default.
• W2034684388 hasConceptScore W2034684388C15744967 @default.
• W2034684388 hasConceptScore W2034684388C169760540 @default.
• W2034684388 hasConceptScore W2034684388C24998067 @default.
• W2034684388 hasConceptScore W2034684388C2777348757 @default.
• W2034684388 hasConceptScore W2034684388C2778373776 @default.
• W2034684388 hasConceptScore W2034684388C2778646069 @default.
• W2034684388 hasConceptScore W2034684388C2778818304 @default.

• next