Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034687402> ?p ?o ?g. }
- W2034687402 endingPage "549" @default.
- W2034687402 startingPage "544" @default.
- W2034687402 abstract "Hepcidin plays a major role in iron homeostasis, but understanding its role has been hampered by the absence of analytical methods for quantification in blood. A commercial ELISA has been developed for serum prohepcidin, a hepcidin precursor, and there is interest in its potential use in the clinical and research arena. We investigated the association between serum prohepcidin concentration and iron absorption in healthy men, and its relationship with iron status in men carrying HFE mutations, hereditary haemochromatosis patients, and pregnant women. Iron absorption was determined in thirty healthy men (fifteen wild-type, fifteen C282Y heterozygote) using the stable isotope red cell incorporation technique. Iron status was measured in 138 healthy men (ninety-one wild-type, forty-seven C282Y heterozygote), six hereditary haemochromatosis patients, and thirteen pregnant women. Mean serum prohepcidin concentrations were 214 ( sd 118) ng/ml [208 ( sd 122) ng/ml in wild-type and 225 ( sd 109) ng/ml in C282Y heterozygotes] in healthy men, 177 ( sd 36) ng/ml in haemochromatosis patients, and 159 ( sd 59) ng/ml in pregnant women. There was no relationship between serum prohepcidin concentration and serum ferritin in any subject groups, nor was it associated with efficiency of iron absorption. Serum prohepcidin is not a useful biomarker for clinical or research purposes." @default.
- W2034687402 created "2016-06-24" @default.
- W2034687402 creator A5009902603 @default.
- W2034687402 creator A5014539210 @default.
- W2034687402 creator A5015653911 @default.
- W2034687402 creator A5024697101 @default.
- W2034687402 creator A5027565959 @default.
- W2034687402 creator A5078987423 @default.
- W2034687402 creator A5081721254 @default.
- W2034687402 creator A5087425245 @default.
- W2034687402 date "2007-03-01" @default.
- W2034687402 modified "2023-10-17" @default.
- W2034687402 title "Serum prohepcidin concentration: no association with iron absorption in healthy men; and no relationship with iron status in men carrying <i>HFE</i> mutations, hereditary haemochromatosis patients undergoing phlebotomy treatment, or pregnant women" @default.
- W2034687402 cites W1761222131 @default.
- W2034687402 cites W1964164688 @default.
- W2034687402 cites W1966383205 @default.
- W2034687402 cites W1980042430 @default.
- W2034687402 cites W1986002998 @default.
- W2034687402 cites W1993789439 @default.
- W2034687402 cites W1998643032 @default.
- W2034687402 cites W2019005560 @default.
- W2034687402 cites W2022175961 @default.
- W2034687402 cites W2025063713 @default.
- W2034687402 cites W2035604252 @default.
- W2034687402 cites W2037635331 @default.
- W2034687402 cites W2043254960 @default.
- W2034687402 cites W2049537345 @default.
- W2034687402 cites W2059080581 @default.
- W2034687402 cites W2063419644 @default.
- W2034687402 cites W2069391281 @default.
- W2034687402 cites W2081098766 @default.
- W2034687402 cites W2090165219 @default.
- W2034687402 cites W2097321850 @default.
- W2034687402 cites W2109100148 @default.
- W2034687402 cites W2110224898 @default.
- W2034687402 cites W2113493898 @default.
- W2034687402 cites W2130382251 @default.
- W2034687402 cites W2147329183 @default.
- W2034687402 cites W2148362837 @default.
- W2034687402 cites W2161998284 @default.
- W2034687402 cites W4249150518 @default.
- W2034687402 doi "https://doi.org/10.1017/s0007114507336829" @default.
- W2034687402 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17313717" @default.
- W2034687402 hasPublicationYear "2007" @default.
- W2034687402 type Work @default.
- W2034687402 sameAs 2034687402 @default.
- W2034687402 citedByCount "88" @default.
- W2034687402 countsByYear W20346874022012 @default.
- W2034687402 countsByYear W20346874022013 @default.
- W2034687402 countsByYear W20346874022014 @default.
- W2034687402 countsByYear W20346874022015 @default.
- W2034687402 countsByYear W20346874022016 @default.
- W2034687402 countsByYear W20346874022017 @default.
- W2034687402 countsByYear W20346874022018 @default.
- W2034687402 countsByYear W20346874022019 @default.
- W2034687402 countsByYear W20346874022020 @default.
- W2034687402 countsByYear W20346874022021 @default.
- W2034687402 crossrefType "journal-article" @default.
- W2034687402 hasAuthorship W2034687402A5009902603 @default.
- W2034687402 hasAuthorship W2034687402A5014539210 @default.
- W2034687402 hasAuthorship W2034687402A5015653911 @default.
- W2034687402 hasAuthorship W2034687402A5024697101 @default.
- W2034687402 hasAuthorship W2034687402A5027565959 @default.
- W2034687402 hasAuthorship W2034687402A5078987423 @default.
- W2034687402 hasAuthorship W2034687402A5081721254 @default.
- W2034687402 hasAuthorship W2034687402A5087425245 @default.
- W2034687402 hasBestOaLocation W20346874021 @default.
- W2034687402 hasConcept C126322002 @default.
- W2034687402 hasConcept C22814914 @default.
- W2034687402 hasConcept C2776590208 @default.
- W2034687402 hasConcept C2776768029 @default.
- W2034687402 hasConcept C2777357209 @default.
- W2034687402 hasConcept C2778248108 @default.
- W2034687402 hasConcept C2778319317 @default.
- W2034687402 hasConcept C2779875672 @default.
- W2034687402 hasConcept C3018783601 @default.
- W2034687402 hasConcept C42407357 @default.
- W2034687402 hasConcept C71924100 @default.
- W2034687402 hasConcept C90924648 @default.
- W2034687402 hasConceptScore W2034687402C126322002 @default.
- W2034687402 hasConceptScore W2034687402C22814914 @default.
- W2034687402 hasConceptScore W2034687402C2776590208 @default.
- W2034687402 hasConceptScore W2034687402C2776768029 @default.
- W2034687402 hasConceptScore W2034687402C2777357209 @default.
- W2034687402 hasConceptScore W2034687402C2778248108 @default.
- W2034687402 hasConceptScore W2034687402C2778319317 @default.
- W2034687402 hasConceptScore W2034687402C2779875672 @default.
- W2034687402 hasConceptScore W2034687402C3018783601 @default.
- W2034687402 hasConceptScore W2034687402C42407357 @default.
- W2034687402 hasConceptScore W2034687402C71924100 @default.
- W2034687402 hasConceptScore W2034687402C90924648 @default.
- W2034687402 hasIssue "3" @default.
- W2034687402 hasLocation W20346874021 @default.
- W2034687402 hasLocation W20346874022 @default.
- W2034687402 hasOpenAccess W2034687402 @default.
- W2034687402 hasPrimaryLocation W20346874021 @default.
- W2034687402 hasRelatedWork W1986987908 @default.
- W2034687402 hasRelatedWork W1996286752 @default.