Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034691110> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2034691110 endingPage "116" @default.
- W2034691110 startingPage "109" @default.
- W2034691110 abstract "The therapeutic effects of a selectin inhibitor against lipopolysaccharide-induced acute lung injury were studied in rabbits by using sialyl Lewis X-oligosaccharide. Lipopolysaccharide-induced acute lung injury, as characterized by an impairment of pulmonary gas exchange, clinically resembles that of the acute respiratory distress syndrome. Delayed treatments with sialyl Lewis X-oligosaccharide (55 mg kg(-1) i.v. bolus injection 0.5, 1 or 2 h after lipopolysaccharide administration+36 mg kg(-1) h(-1) i.v. infusion for 5.5, 5 or 4 h, respectively) prevented the lipopolysaccharide-induced impairments in pulmonary gas exchange, as well as the accumulation of polymorphonuclear leukocytes in the lung tissue. In contrast, this agent had no significant effects on lipopolysaccharide-induced systemic hypotension, the decrease in the number of circulating white blood cells and platelets or the decline in blood pH. This is the first demonstration that sialyl Lewis X-oligosaccharide is effective against the impairments in pulmonary gas exchange even if administered 0.5, 1 or 2 h following the lipopolysaccharide injection." @default.
- W2034691110 created "2016-06-24" @default.
- W2034691110 creator A5022071658 @default.
- W2034691110 creator A5024842964 @default.
- W2034691110 creator A5050938017 @default.
- W2034691110 creator A5056358182 @default.
- W2034691110 date "2000-03-01" @default.
- W2034691110 modified "2023-10-17" @default.
- W2034691110 title "The effects of delayed treatment with sialyl Lewis X against lipopolysaccharide-induced acute lung injury in rabbits" @default.
- W2034691110 cites W1559927414 @default.
- W2034691110 cites W1949441280 @default.
- W2034691110 cites W1984549408 @default.
- W2034691110 cites W2007537853 @default.
- W2034691110 cites W2032753448 @default.
- W2034691110 cites W2066702261 @default.
- W2034691110 cites W2074255803 @default.
- W2034691110 cites W2077214826 @default.
- W2034691110 cites W2084351211 @default.
- W2034691110 cites W2087020806 @default.
- W2034691110 cites W2108550131 @default.
- W2034691110 cites W2109275053 @default.
- W2034691110 cites W2131339314 @default.
- W2034691110 cites W2132925738 @default.
- W2034691110 cites W2144459905 @default.
- W2034691110 cites W2146841277 @default.
- W2034691110 cites W2233495136 @default.
- W2034691110 cites W2411164904 @default.
- W2034691110 cites W4246991801 @default.
- W2034691110 cites W4250658292 @default.
- W2034691110 doi "https://doi.org/10.1016/s0014-2999(00)00099-6" @default.
- W2034691110 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10748279" @default.
- W2034691110 hasPublicationYear "2000" @default.
- W2034691110 type Work @default.
- W2034691110 sameAs 2034691110 @default.
- W2034691110 citedByCount "0" @default.
- W2034691110 crossrefType "journal-article" @default.
- W2034691110 hasAuthorship W2034691110A5022071658 @default.
- W2034691110 hasAuthorship W2034691110A5024842964 @default.
- W2034691110 hasAuthorship W2034691110A5050938017 @default.
- W2034691110 hasAuthorship W2034691110A5056358182 @default.
- W2034691110 hasConcept C126322002 @default.
- W2034691110 hasConcept C141983124 @default.
- W2034691110 hasConcept C155619193 @default.
- W2034691110 hasConcept C185592680 @default.
- W2034691110 hasConcept C203014093 @default.
- W2034691110 hasConcept C2776914184 @default.
- W2034691110 hasConcept C2777117008 @default.
- W2034691110 hasConcept C2777714996 @default.
- W2034691110 hasConcept C2777726330 @default.
- W2034691110 hasConcept C2778754761 @default.
- W2034691110 hasConcept C42219234 @default.
- W2034691110 hasConcept C43376680 @default.
- W2034691110 hasConcept C55493867 @default.
- W2034691110 hasConcept C71924100 @default.
- W2034691110 hasConcept C89560881 @default.
- W2034691110 hasConcept C98274493 @default.
- W2034691110 hasConceptScore W2034691110C126322002 @default.
- W2034691110 hasConceptScore W2034691110C141983124 @default.
- W2034691110 hasConceptScore W2034691110C155619193 @default.
- W2034691110 hasConceptScore W2034691110C185592680 @default.
- W2034691110 hasConceptScore W2034691110C203014093 @default.
- W2034691110 hasConceptScore W2034691110C2776914184 @default.
- W2034691110 hasConceptScore W2034691110C2777117008 @default.
- W2034691110 hasConceptScore W2034691110C2777714996 @default.
- W2034691110 hasConceptScore W2034691110C2777726330 @default.
- W2034691110 hasConceptScore W2034691110C2778754761 @default.
- W2034691110 hasConceptScore W2034691110C42219234 @default.
- W2034691110 hasConceptScore W2034691110C43376680 @default.
- W2034691110 hasConceptScore W2034691110C55493867 @default.
- W2034691110 hasConceptScore W2034691110C71924100 @default.
- W2034691110 hasConceptScore W2034691110C89560881 @default.
- W2034691110 hasConceptScore W2034691110C98274493 @default.
- W2034691110 hasIssue "1-2" @default.
- W2034691110 hasLocation W20346911101 @default.
- W2034691110 hasLocation W20346911102 @default.
- W2034691110 hasOpenAccess W2034691110 @default.
- W2034691110 hasPrimaryLocation W20346911101 @default.
- W2034691110 hasRelatedWork W1953852588 @default.
- W2034691110 hasRelatedWork W1999558856 @default.
- W2034691110 hasRelatedWork W2003565154 @default.
- W2034691110 hasRelatedWork W2004673806 @default.
- W2034691110 hasRelatedWork W2034691110 @default.
- W2034691110 hasRelatedWork W2473060709 @default.
- W2034691110 hasRelatedWork W2748952813 @default.
- W2034691110 hasRelatedWork W2899084033 @default.
- W2034691110 hasRelatedWork W3008296331 @default.
- W2034691110 hasRelatedWork W4290345173 @default.
- W2034691110 hasVolume "392" @default.
- W2034691110 isParatext "false" @default.
- W2034691110 isRetracted "false" @default.
- W2034691110 magId "2034691110" @default.
- W2034691110 workType "article" @default.