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- W2034693872 abstract "Young rabbits were given daily i.p. injections of saline, or 20 mg/kg of one of two drugs related to amiodarone, but not containing iodine. L8040 is a brominated thiophene derivative; L8462 contains no halogen. Both drugs caused a prolongation of the duration of the cardiac action potential, an effect characteristic of amiodarone. Unlike amiodarone, neither drug caused a fall in heart weight expressed as a percentage of body weight, but both drugs reduced the rate of growth. L8462 protected anaesthetised guinea pigs against ouabain-induced ventricular fibrillation and increased the lethal dose." @default.
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- W2034693872 date "1974-02-01" @default.
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- W2034693872 title "The effect on cardiac muscle of two drugs related to amiodarone, L8040 and L8462" @default.
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- W2034693872 doi "https://doi.org/10.1016/0014-2999(74)90056-9" @default.
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