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- W2034694783 abstract "Antigen preparations of Plasmodium chabaudi parasites enriched in merozoites and schizonts, obtained from in vitro culture, and combined with saponin protected C57BL/6J mice from P. chabaudi infection as judged by reduced primary parasitemias and recrudescences. Sera passively transferred from immunized and untreated mice after a challenge infection were more protective in recipients than serum from normal mice. Mice treated with antilymphocyte serum during immunization did not develop as strong an immunity to infection as did controls treated with normal serum. Immunized mice had depressed delayed-type hypersensitivity reactions to malarial antigen but increased serum titers of malarial antibody (measured by imniunofluorescence) after challenge with P. chabaudi when compared to immunized mice which remained unchallenged. The protective activity of sera from various groups of mice did not necessarily correlate with the serum antibody titers." @default.
- W2034694783 created "2016-06-24" @default.
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- W2034694783 date "1980-06-01" @default.
- W2034694783 modified "2023-09-25" @default.
- W2034694783 title "Plasmodium chabaudi: Humoral and cell-mediated responses of immunized mice" @default.
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- W2034694783 doi "https://doi.org/10.1016/0014-4894(80)90078-8" @default.
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