Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034697570> ?p ?o ?g. }
- W2034697570 endingPage "268" @default.
- W2034697570 startingPage "261" @default.
- W2034697570 abstract "We have investigated the involvement of store-operated Ca2+ entry (SOCE) in the abnormal platelet Ca2+ homeostasis in patients with non insulin-dependent diabetes mellitus (NIDDM). In a medium containing 180 mg/dL glucose, platelets from NIDDM patients showed an increased SOCE compared to controls. We found that tyrosine phosphorylation was elevated in platelets from NIDDM patients. Consistent with this, the activity of the tyrosine kinase pp60src is enhanced in platelets from diabetic patients. When the experiments were performed in a medium containing 90 mg/dL both, SOCE and pp60src activity, were similar to those found in control platelets. Our results indicate that SOCE is altered in platelets from NIDDM patients probably due to the increased activity of the tyrosine kinase pp60src. Both, SOCE and pp60src activity in platelets from NIDDM patients are more susceptible to the extracellular glucose concentration, which seems to be involved in the dysfunction of these mechanisms." @default.
- W2034697570 created "2016-06-24" @default.
- W2034697570 creator A5002282410 @default.
- W2034697570 creator A5030715778 @default.
- W2034697570 creator A5036708850 @default.
- W2034697570 creator A5062753801 @default.
- W2034697570 creator A5069573416 @default.
- W2034697570 creator A5080498077 @default.
- W2034697570 date "2004-12-01" @default.
- W2034697570 modified "2023-09-25" @default.
- W2034697570 title "Store-operated Ca2+ entry and tyrosine kinase pp60src hyperactivity are modulated by hyperglycemia in platelets from patients with non insulin-dependent diabetes mellitus" @default.
- W2034697570 cites W1966050211 @default.
- W2034697570 cites W1980060407 @default.
- W2034697570 cites W1981810445 @default.
- W2034697570 cites W1985086376 @default.
- W2034697570 cites W1987015688 @default.
- W2034697570 cites W1993913708 @default.
- W2034697570 cites W2012347765 @default.
- W2034697570 cites W2017280054 @default.
- W2034697570 cites W2027094257 @default.
- W2034697570 cites W2030968909 @default.
- W2034697570 cites W2044666380 @default.
- W2034697570 cites W2047046251 @default.
- W2034697570 cites W2049361557 @default.
- W2034697570 cites W2049647579 @default.
- W2034697570 cites W2059750107 @default.
- W2034697570 cites W2064583017 @default.
- W2034697570 cites W2068727414 @default.
- W2034697570 cites W2079375868 @default.
- W2034697570 cites W2081726929 @default.
- W2034697570 cites W2084526056 @default.
- W2034697570 cites W2088650647 @default.
- W2034697570 cites W2093928625 @default.
- W2034697570 cites W2096531477 @default.
- W2034697570 cites W2100837269 @default.
- W2034697570 cites W2114382763 @default.
- W2034697570 cites W2141260882 @default.
- W2034697570 cites W2151178365 @default.
- W2034697570 cites W2171577896 @default.
- W2034697570 cites W2175831347 @default.
- W2034697570 cites W2318189791 @default.
- W2034697570 cites W4249375250 @default.
- W2034697570 doi "https://doi.org/10.1016/j.abb.2004.09.034" @default.
- W2034697570 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15542065" @default.
- W2034697570 hasPublicationYear "2004" @default.
- W2034697570 type Work @default.
- W2034697570 sameAs 2034697570 @default.
- W2034697570 citedByCount "42" @default.
- W2034697570 countsByYear W20346975702012 @default.
- W2034697570 countsByYear W20346975702014 @default.
- W2034697570 countsByYear W20346975702015 @default.
- W2034697570 countsByYear W20346975702016 @default.
- W2034697570 countsByYear W20346975702017 @default.
- W2034697570 countsByYear W20346975702018 @default.
- W2034697570 countsByYear W20346975702019 @default.
- W2034697570 crossrefType "journal-article" @default.
- W2034697570 hasAuthorship W2034697570A5002282410 @default.
- W2034697570 hasAuthorship W2034697570A5030715778 @default.
- W2034697570 hasAuthorship W2034697570A5036708850 @default.
- W2034697570 hasAuthorship W2034697570A5062753801 @default.
- W2034697570 hasAuthorship W2034697570A5069573416 @default.
- W2034697570 hasAuthorship W2034697570A5080498077 @default.
- W2034697570 hasConcept C126322002 @default.
- W2034697570 hasConcept C134018914 @default.
- W2034697570 hasConcept C170493617 @default.
- W2034697570 hasConcept C184235292 @default.
- W2034697570 hasConcept C185592680 @default.
- W2034697570 hasConcept C2776165026 @default.
- W2034697570 hasConcept C2777553839 @default.
- W2034697570 hasConcept C2779306644 @default.
- W2034697570 hasConcept C28406088 @default.
- W2034697570 hasConcept C3018697912 @default.
- W2034697570 hasConcept C42362537 @default.
- W2034697570 hasConcept C55493867 @default.
- W2034697570 hasConcept C555293320 @default.
- W2034697570 hasConcept C63645605 @default.
- W2034697570 hasConcept C71924100 @default.
- W2034697570 hasConcept C89560881 @default.
- W2034697570 hasConceptScore W2034697570C126322002 @default.
- W2034697570 hasConceptScore W2034697570C134018914 @default.
- W2034697570 hasConceptScore W2034697570C170493617 @default.
- W2034697570 hasConceptScore W2034697570C184235292 @default.
- W2034697570 hasConceptScore W2034697570C185592680 @default.
- W2034697570 hasConceptScore W2034697570C2776165026 @default.
- W2034697570 hasConceptScore W2034697570C2777553839 @default.
- W2034697570 hasConceptScore W2034697570C2779306644 @default.
- W2034697570 hasConceptScore W2034697570C28406088 @default.
- W2034697570 hasConceptScore W2034697570C3018697912 @default.
- W2034697570 hasConceptScore W2034697570C42362537 @default.
- W2034697570 hasConceptScore W2034697570C55493867 @default.
- W2034697570 hasConceptScore W2034697570C555293320 @default.
- W2034697570 hasConceptScore W2034697570C63645605 @default.
- W2034697570 hasConceptScore W2034697570C71924100 @default.
- W2034697570 hasConceptScore W2034697570C89560881 @default.
- W2034697570 hasIssue "2" @default.
- W2034697570 hasLocation W20346975701 @default.
- W2034697570 hasLocation W20346975702 @default.
- W2034697570 hasOpenAccess W2034697570 @default.