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- W2034699918 abstract "Abstract Aconitase and TPN-linked iso citric dehydrogenase activities in the supernatant fraction of the gingiva and alveolar bone of scorbutic guinea pigs were evaluated. The activities of both enzymes in the heart, liver, kidney, adrenal gland, pancreas, spleen and femoral cortex were also studied. The aconitase activity of the kidney, alveolar bone, femur cortex and heart decreased to about 75 per cent of the normal value after 3 weeks of scorbutic regime. However, the other tissues did not exhibit significant changes. Elevated citrate level was also found in kidney, alveolar bone and femur cortex in which the aconitase activity was markedly decreased. Prolonged administration of insulin to scorbutic animals restored both the depressed aconitase activity and the elevated citrate content in the kidney and bone tissues significantly to normal level. No significant change in the activity of iso citric dehydrogenase was observed in any of the tissues of scorbutic animals." @default.
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- W2034699918 date "1965-03-01" @default.
- W2034699918 modified "2023-09-27" @default.
- W2034699918 title "Citric acid metabolism in scurvy" @default.
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- W2034699918 doi "https://doi.org/10.1016/0003-9969(65)90032-4" @default.
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