FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034707118> ?p ?o ?g. }

• W2034707118 endingPage "31" @default.
• W2034707118 startingPage "25" @default.
• W2034707118 abstract "Harmless antigens encountered on the mucosal surface are normally tolerated in the sense that they do not induce inflammatory immune responses. Oral tolerance is the type of mucosal immune regulation that prevents inflammatory reactions to food proteins. However, parasites and invasive microorganisms at the mucosal surfaces must be recognised and dealt with in a proper manner. The immune system does so by cross-regulating the response where it either produces IgA to exclude invasion, IgE to fight parasites, or IgG to destroy the invasive organisms. Allergy is an anti-parasitic reaction to a misinterpreted but harmless antigen. This lack of tolerance induction is influenced by genetic factors controlling the amount of interleukin (IL)-4 produced initially in the immune response. IL-4 directs B-cells to produce IgE, induces naive T-cells to become IL-4 producing T-helper cells (Th2 cells) and prevent other T-cells from entering into the IFN-γ-producing Th1 pathway. Long lasting Th2 clones lose their IL-12 responsiveness and can no longer be induced to produce IFN-γ thus they are locked in an allergy inducing Th2 phenotype. Environmental factors play on the genetic background and influence the outcome of the immune response. Mucosal tolerance depends on an intact mucosal surface, is influenced by the age of the subject, and can be manipulated through antigen dose and place of entry. Immune-manipulating therapy may be more successful in primary than in secondary prevention of allergy." @default.
• W2034707118 created "2016-06-24" @default.
• W2034707118 creator A5064328634 @default.
• W2034707118 date "1997-11-01" @default.
• W2034707118 modified "2023-10-05" @default.
• W2034707118 title "Why are we not all allergic: basic mechanisms for tolerance development" @default.
• W2034707118 cites W1514162038 @default.
• W2034707118 cites W1576553969 @default.
• W2034707118 cites W1584754204 @default.
• W2034707118 cites W1590141303 @default.
• W2034707118 cites W1658116990 @default.
• W2034707118 cites W1847326209 @default.
• W2034707118 cites W1963773608 @default.
• W2034707118 cites W1964719757 @default.
• W2034707118 cites W1966656613 @default.
• W2034707118 cites W1968274103 @default.
• W2034707118 cites W1970959631 @default.
• W2034707118 cites W1972922050 @default.
• W2034707118 cites W1976195770 @default.
• W2034707118 cites W1976602591 @default.
• W2034707118 cites W1978033927 @default.
• W2034707118 cites W1988508943 @default.
• W2034707118 cites W2007435219 @default.
• W2034707118 cites W2018664427 @default.
• W2034707118 cites W2027724236 @default.
• W2034707118 cites W2031102525 @default.
• W2034707118 cites W2035088845 @default.
• W2034707118 cites W2051579898 @default.
• W2034707118 cites W2064716896 @default.
• W2034707118 cites W2066943538 @default.
• W2034707118 cites W2077397102 @default.
• W2034707118 cites W2077654197 @default.
• W2034707118 cites W2079313807 @default.
• W2034707118 cites W2083846343 @default.
• W2034707118 cites W2086389480 @default.
• W2034707118 cites W2087326265 @default.
• W2034707118 cites W2094199329 @default.
• W2034707118 cites W2099450563 @default.
• W2034707118 cites W2102153142 @default.
• W2034707118 cites W2104964332 @default.
• W2034707118 cites W2109506765 @default.
• W2034707118 cites W2114104671 @default.
• W2034707118 cites W2115140326 @default.
• W2034707118 cites W2159997401 @default.
• W2034707118 cites W2161362125 @default.
• W2034707118 cites W2334615221 @default.
• W2034707118 cites W2387618264 @default.
• W2034707118 cites W2406433139 @default.
• W2034707118 doi "https://doi.org/10.1016/s1382-6689(97)10037-0" @default.
• W2034707118 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21781795" @default.
• W2034707118 hasPublicationYear "1997" @default.
• W2034707118 type Work @default.
• W2034707118 sameAs 2034707118 @default.
• W2034707118 citedByCount "8" @default.
• W2034707118 countsByYear W20347071182016 @default.
• W2034707118 countsByYear W20347071182018 @default.
• W2034707118 crossrefType "journal-article" @default.
• W2034707118 hasAuthorship W2034707118A5064328634 @default.
• W2034707118 hasConcept C104317684 @default.
• W2034707118 hasConcept C127716648 @default.
• W2034707118 hasConcept C141105273 @default.
• W2034707118 hasConcept C147483822 @default.
• W2034707118 hasConcept C159654299 @default.
• W2034707118 hasConcept C203014093 @default.
• W2034707118 hasConcept C207480886 @default.
• W2034707118 hasConcept C2776027960 @default.
• W2034707118 hasConcept C2776953665 @default.
• W2034707118 hasConcept C2777702733 @default.
• W2034707118 hasConcept C2910153128 @default.
• W2034707118 hasConcept C54355233 @default.
• W2034707118 hasConcept C86803240 @default.
• W2034707118 hasConcept C8891405 @default.
• W2034707118 hasConceptScore W2034707118C104317684 @default.
• W2034707118 hasConceptScore W2034707118C127716648 @default.
• W2034707118 hasConceptScore W2034707118C141105273 @default.
• W2034707118 hasConceptScore W2034707118C147483822 @default.
• W2034707118 hasConceptScore W2034707118C159654299 @default.
• W2034707118 hasConceptScore W2034707118C203014093 @default.
• W2034707118 hasConceptScore W2034707118C207480886 @default.
• W2034707118 hasConceptScore W2034707118C2776027960 @default.
• W2034707118 hasConceptScore W2034707118C2776953665 @default.
• W2034707118 hasConceptScore W2034707118C2777702733 @default.
• W2034707118 hasConceptScore W2034707118C2910153128 @default.
• W2034707118 hasConceptScore W2034707118C54355233 @default.
• W2034707118 hasConceptScore W2034707118C86803240 @default.
• W2034707118 hasConceptScore W2034707118C8891405 @default.
• W2034707118 hasIssue "1-2" @default.
• W2034707118 hasLocation W20347071181 @default.
• W2034707118 hasLocation W20347071182 @default.
• W2034707118 hasOpenAccess W2034707118 @default.
• W2034707118 hasPrimaryLocation W20347071181 @default.
• W2034707118 hasRelatedWork W1571696686 @default.
• W2034707118 hasRelatedWork W1967072041 @default.
• W2034707118 hasRelatedWork W1993652955 @default.
• W2034707118 hasRelatedWork W2009993815 @default.
• W2034707118 hasRelatedWork W2013304482 @default.
• W2034707118 hasRelatedWork W2029386087 @default.
• W2034707118 hasRelatedWork W2034707118 @default.

• next