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- W2034707706 abstract "GABAC and GABAA receptors co-exist in retinal bipolar cells. In the present study the effects of zinc on the kinetics of currents mediated by GABAC and GABAA receptors were investigated in isolated carp bipolar cells, using whole-cell patch-clamp technique. We observed for the first time that zinc exerted opposite effects on kinetics of the GABAC and GABAA responses: zinc significantly slowed down activation and desensitization of the GABAC response, but accelerated those of the GABAA response; zinc dramatically accelerated deactivation of the GABAC response, whereas it had no apparent effect on deactivation of the GABAA response. These results suggest that zinc may be functionally important in regulating retinal signal transmission." @default.
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- W2034707706 date "1999-08-01" @default.
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- W2034707706 title "Zn2+ differentially modulates kinetics of GABAC vs GABAA receptors in carp retinal bipolar cells" @default.
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- W2034707706 doi "https://doi.org/10.1097/00001756-199908200-00028" @default.
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