FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034709522> ?p ?o ?g. }

• W2034709522 endingPage "2540" @default.
• W2034709522 startingPage "2534" @default.
• W2034709522 abstract "Free energy profiles for insertion of a hydrophobic transmembrane protein α-helix (M2 from CFTR) into a lipid bilayer have been calculated using coarse-grained molecular dynamics simulations and umbrella sampling to yield potentials of mean force along a reaction path corresponding to translation of a helix across a lipid bilayer. The calculated free energy of insertion is smaller when a bilayer with a thinner hydrophobic region is used. The free energies of insertion from the potentials of mean force are compared with those derived from a number of hydrophobicity scales and with those derived from translocon-mediated insertion. This comparison supports recent models of translocon-mediated insertion and in particular suggests that: 1), helices in an about-to-be-inserted state may be located in a hydrophobic region somewhat thinner than the core of a lipid bilayer; and/or 2), helices in a not-to-be-inserted state may experience an environment more akin (e.g., in polarity/hydrophobicity) to the bilayer/water interface than to bulk water." @default.
• W2034709522 created "2016-06-24" @default.
• W2034709522 creator A5027490511 @default.
• W2034709522 creator A5030984146 @default.
• W2034709522 creator A5041718990 @default.
• W2034709522 creator A5081320135 @default.
• W2034709522 date "2010-10-01" @default.
• W2034709522 modified "2023-10-12" @default.
• W2034709522 title "The Energetics of Transmembrane Helix Insertion into a Lipid Bilayer" @default.
• W2034709522 cites W1969455492 @default.
• W2034709522 cites W1971456069 @default.
• W2034709522 cites W1973585747 @default.
• W2034709522 cites W1974789047 @default.
• W2034709522 cites W1988495699 @default.
• W2034709522 cites W1995827482 @default.
• W2034709522 cites W1997501696 @default.
• W2034709522 cites W2002128187 @default.
• W2034709522 cites W2015538142 @default.
• W2034709522 cites W2020570580 @default.
• W2034709522 cites W2025859600 @default.
• W2034709522 cites W2026593599 @default.
• W2034709522 cites W2029667189 @default.
• W2034709522 cites W2031282085 @default.
• W2034709522 cites W2035266068 @default.
• W2034709522 cites W2036274542 @default.
• W2034709522 cites W2038302435 @default.
• W2034709522 cites W2041499944 @default.
• W2034709522 cites W2043693398 @default.
• W2034709522 cites W2049286183 @default.
• W2034709522 cites W2051864856 @default.
• W2034709522 cites W2055154757 @default.
• W2034709522 cites W2060097208 @default.
• W2034709522 cites W2064552416 @default.
• W2034709522 cites W2076254891 @default.
• W2034709522 cites W2076515696 @default.
• W2034709522 cites W2077455410 @default.
• W2034709522 cites W2078481695 @default.
• W2034709522 cites W2080985792 @default.
• W2034709522 cites W2086363028 @default.
• W2034709522 cites W2086461949 @default.
• W2034709522 cites W2107066422 @default.
• W2034709522 cites W2109677076 @default.
• W2034709522 cites W2112154906 @default.
• W2034709522 cites W2119267663 @default.
• W2034709522 cites W2123768693 @default.
• W2034709522 cites W2127162389 @default.
• W2034709522 cites W2138671124 @default.
• W2034709522 cites W2142532813 @default.
• W2034709522 cites W2144179513 @default.
• W2034709522 cites W2146752518 @default.
• W2034709522 cites W2147691794 @default.
• W2034709522 cites W2148138913 @default.
• W2034709522 cites W2152270594 @default.
• W2034709522 cites W2158420950 @default.
• W2034709522 cites W2170193142 @default.
• W2034709522 cites W2171742422 @default.
• W2034709522 doi "https://doi.org/10.1016/j.bpj.2010.08.002" @default.
• W2034709522 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2955506" @default.
• W2034709522 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20959094" @default.
• W2034709522 hasPublicationYear "2010" @default.
• W2034709522 type Work @default.
• W2034709522 sameAs 2034709522 @default.
• W2034709522 citedByCount "23" @default.
• W2034709522 countsByYear W20347095222012 @default.
• W2034709522 countsByYear W20347095222013 @default.
• W2034709522 countsByYear W20347095222014 @default.
• W2034709522 countsByYear W20347095222015 @default.
• W2034709522 countsByYear W20347095222016 @default.
• W2034709522 countsByYear W20347095222018 @default.
• W2034709522 countsByYear W20347095222019 @default.
• W2034709522 countsByYear W20347095222021 @default.
• W2034709522 countsByYear W20347095222022 @default.
• W2034709522 countsByYear W20347095222023 @default.
• W2034709522 crossrefType "journal-article" @default.
• W2034709522 hasAuthorship W2034709522A5027490511 @default.
• W2034709522 hasAuthorship W2034709522A5030984146 @default.
• W2034709522 hasAuthorship W2034709522A5041718990 @default.
• W2034709522 hasAuthorship W2034709522A5081320135 @default.
• W2034709522 hasBestOaLocation W20347095221 @default.
• W2034709522 hasConcept C118892022 @default.
• W2034709522 hasConcept C12554922 @default.
• W2034709522 hasConcept C128747166 @default.
• W2034709522 hasConcept C144647389 @default.
• W2034709522 hasConcept C147597530 @default.
• W2034709522 hasConcept C159467904 @default.
• W2034709522 hasConcept C170493617 @default.
• W2034709522 hasConcept C175634916 @default.
• W2034709522 hasConcept C185592680 @default.
• W2034709522 hasConcept C18903297 @default.
• W2034709522 hasConcept C192157962 @default.
• W2034709522 hasConcept C199229279 @default.
• W2034709522 hasConcept C24530287 @default.
• W2034709522 hasConcept C2778530040 @default.
• W2034709522 hasConcept C2779965526 @default.
• W2034709522 hasConcept C39944091 @default.
• W2034709522 hasConcept C41625074 @default.
• W2034709522 hasConcept C55493867 @default.
• W2034709522 hasConcept C59593255 @default.

• next