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- W2034721639 abstract "Oxygen affinity (expressed as oxygen half saturation pressure P;g) and red cell 2,3-diphosphoglycerate (2,3 DPG) concentration of miniature pig blood was examined in fetuses (95–110 days gestational age) and piglets from birth until 50 days post partum. Fetuses had the highest oxygen affinity (P50 23 mm Hg) and lowest 2,3 DPG concentration (2.40 mM 2,3 DPG/1, RBC). Both P50 and 2,3 DPG concentration increased rapidly during the first week after birth towards adult levels. Haemoglobin electrophoresis did not show different behaviour of haemoglobin obtained from foetal, postnatal or adult pig blood. The oxygen equilibrium curves of the respective dialysed haemoglobin solutions were identical and upon addition of 2,3 DPG the same decrease in oxygen affinity was observed. It is concluded that the postnatal decrease in pig blood oxygen affinity is caused by a concomitant increase in red cell 2,3 DPG concentration." @default.
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- W2034721639 date "1973-11-01" @default.
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- W2034721639 title "Changes in red cell 2,3-diphosphoglycerate concentration as cause of the postnatal decrease of pig blood oxygen affinity" @default.
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- W2034721639 doi "https://doi.org/10.1016/0034-5687(73)90074-1" @default.
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