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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034731532> ?p ?o ?g. }

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• W2034731532 startingPage "1555" @default.
• W2034731532 abstract "The 3-(4-cyano-3-trifluoromethylphenyl)-5,5-dimethylthiohydantoin derivatives which have carboxy-terminal side chains were synthesized and their agonistic/antagonistic activities against androgen receptor (AR) measured. Among them, compound 13b showed antagonistic activity (IC50=130 nM) with no agonistic activity even at 10000 nM. This compound exhibited significant metabolic stability and oral antiandrogenic activity (ED50=7 mg/kg)." @default.
• W2034731532 created "2016-06-24" @default.
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• W2034731532 date "2008-01-01" @default.
• W2034731532 modified "2023-10-16" @default.
• W2034731532 title "Discovery of an Orally-Active Nonsteroidal Androgen Receptor Pure Antagonist and the Structure-Activity Relationships of Its Derivatives" @default.
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• W2034731532 doi "https://doi.org/10.1248/cpb.56.1555" @default.
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