Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034747844> ?p ?o ?g. }
- W2034747844 endingPage "300" @default.
- W2034747844 startingPage "295" @default.
- W2034747844 abstract "BACKGROUND: AMD3100, a selective antagonist of CXCR4, rapidly mobilizes CD34+ hematopoietic progenitor cells (HPCs) from marrow to peripheral blood with minimal side effects. STUDY DESIGN AND METHODS: To further investigate potential clinical utility of AMD3100 for CD34+ cell mobilization and collection, a Phase I study in normal volunteers was performed examining single‐dose administration of AMD3100 alone and in combination with a standard 5‐day granulocyte–colony‐stimulating factor (G–CSF) regimen. RESULTS: AMD3100 (160 µg/kg × 1 on Day 5) significantly increased both G–CSF‐stimulated (10 µg/kg/day) mobilization of CD34+ cells (3.8‐fold) and leukapheresis yield of CD34+ cells. Moreover, collection of CD34+ cells was comparable between individuals mobilized by a single‐dose regimen of AMD3100 (240 µg/kg) and individuals mobilized with a 5‐day regimen of G–CSF. AMD3100‐mobilized leukapheresis products contained significantly greater numbers of T and B cells compared to G–CSF‐stimulated leukapheresis products. CONCLUSION: These findings indicate that AMD3100 can be used alone or as an adjunct to G–CSF to mobilize cells for HPC transplantation." @default.
- W2034747844 created "2016-06-24" @default.
- W2034747844 creator A5013533743 @default.
- W2034747844 creator A5013754928 @default.
- W2034747844 creator A5015520404 @default.
- W2034747844 creator A5023854052 @default.
- W2034747844 creator A5029657694 @default.
- W2034747844 creator A5034076988 @default.
- W2034747844 creator A5038161052 @default.
- W2034747844 creator A5043805146 @default.
- W2034747844 creator A5054532615 @default.
- W2034747844 creator A5088629737 @default.
- W2034747844 date "2005-03-01" @default.
- W2034747844 modified "2023-10-15" @default.
- W2034747844 title "Augmented mobilization and collection of CD34+ hematopoietic cells from normal human volunteers stimulated with granulocyte-colony-stimulating factor by single-dose administration of AMD3100, a CXCR4 antagonist" @default.
- W2034747844 cites W1501974099 @default.
- W2034747844 cites W1504660023 @default.
- W2034747844 cites W1532087698 @default.
- W2034747844 cites W1536989454 @default.
- W2034747844 cites W154306038 @default.
- W2034747844 cites W174869347 @default.
- W2034747844 cites W1900214176 @default.
- W2034747844 cites W1985965995 @default.
- W2034747844 cites W2024835620 @default.
- W2034747844 cites W2025524577 @default.
- W2034747844 cites W2030846042 @default.
- W2034747844 cites W2034768868 @default.
- W2034747844 cites W2041232976 @default.
- W2034747844 cites W2069192477 @default.
- W2034747844 cites W2084074931 @default.
- W2034747844 cites W2092084671 @default.
- W2034747844 cites W2094115571 @default.
- W2034747844 cites W2105608776 @default.
- W2034747844 cites W2110687581 @default.
- W2034747844 cites W2114741924 @default.
- W2034747844 cites W2114805956 @default.
- W2034747844 cites W2118168943 @default.
- W2034747844 cites W2121763019 @default.
- W2034747844 cites W2124090816 @default.
- W2034747844 cites W2125887123 @default.
- W2034747844 cites W2129680615 @default.
- W2034747844 cites W2130966806 @default.
- W2034747844 cites W2141837666 @default.
- W2034747844 cites W2144456609 @default.
- W2034747844 cites W2158470148 @default.
- W2034747844 cites W2169584423 @default.
- W2034747844 doi "https://doi.org/10.1111/j.1537-2995.2005.04222.x" @default.
- W2034747844 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15752146" @default.
- W2034747844 hasPublicationYear "2005" @default.
- W2034747844 type Work @default.
- W2034747844 sameAs 2034747844 @default.
- W2034747844 citedByCount "224" @default.
- W2034747844 countsByYear W20347478442012 @default.
- W2034747844 countsByYear W20347478442013 @default.
- W2034747844 countsByYear W20347478442014 @default.
- W2034747844 countsByYear W20347478442015 @default.
- W2034747844 countsByYear W20347478442016 @default.
- W2034747844 countsByYear W20347478442017 @default.
- W2034747844 countsByYear W20347478442018 @default.
- W2034747844 countsByYear W20347478442019 @default.
- W2034747844 countsByYear W20347478442020 @default.
- W2034747844 countsByYear W20347478442021 @default.
- W2034747844 countsByYear W20347478442022 @default.
- W2034747844 countsByYear W20347478442023 @default.
- W2034747844 crossrefType "journal-article" @default.
- W2034747844 hasAuthorship W2034747844A5013533743 @default.
- W2034747844 hasAuthorship W2034747844A5013754928 @default.
- W2034747844 hasAuthorship W2034747844A5015520404 @default.
- W2034747844 hasAuthorship W2034747844A5023854052 @default.
- W2034747844 hasAuthorship W2034747844A5029657694 @default.
- W2034747844 hasAuthorship W2034747844A5034076988 @default.
- W2034747844 hasAuthorship W2034747844A5038161052 @default.
- W2034747844 hasAuthorship W2034747844A5043805146 @default.
- W2034747844 hasAuthorship W2034747844A5054532615 @default.
- W2034747844 hasAuthorship W2034747844A5088629737 @default.
- W2034747844 hasBestOaLocation W20347478441 @default.
- W2034747844 hasConcept C10205521 @default.
- W2034747844 hasConcept C109159458 @default.
- W2034747844 hasConcept C126322002 @default.
- W2034747844 hasConcept C129470790 @default.
- W2034747844 hasConcept C13373296 @default.
- W2034747844 hasConcept C16685009 @default.
- W2034747844 hasConcept C201750760 @default.
- W2034747844 hasConcept C203014093 @default.
- W2034747844 hasConcept C2776694085 @default.
- W2034747844 hasConcept C2777371436 @default.
- W2034747844 hasConcept C2777767877 @default.
- W2034747844 hasConcept C2777983669 @default.
- W2034747844 hasConcept C2778828106 @default.
- W2034747844 hasConcept C28328180 @default.
- W2034747844 hasConcept C2911091166 @default.
- W2034747844 hasConcept C71924100 @default.
- W2034747844 hasConcept C86803240 @default.
- W2034747844 hasConcept C8891405 @default.
- W2034747844 hasConcept C95444343 @default.
- W2034747844 hasConceptScore W2034747844C10205521 @default.
- W2034747844 hasConceptScore W2034747844C109159458 @default.
- W2034747844 hasConceptScore W2034747844C126322002 @default.