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• W2034750552 startingPage "1683" @default.
• W2034750552 abstract "Arginine-rich proteins (e.g., lysozyme) or poly-l-arginine peptides have been suggested as solvating and dispersing agents for single-wall carbon nanotubes (CNTs) in water. In addition, protein structure–function in porous and hydrophobic materials is of broad interest. The amino acid residue, arginine (Arg+), has been implicated as an important mediator of protein/peptide–CNT interactions. To understand the structural and thermodynamic aspects of this interaction at the molecular level, we employ molecular dynamics (MD) simulations of the protein lysozyme in the interior of a CNT, as well as of free solutions of Arg+ in the presence of a CNT. To dissect the Arg+–CNT interaction further, we also perform simulations of aqueous solutions of the guanidinium ion (Gdm+) and the norvaline (Nva) residue in the presence of a CNT. We show that the interactions of lysozyme with the CNT are mediated by the surface Arg+ residues. The strong interaction of Arg+ residue with the CNT is primarily driven by the favorable interactions of the Gdm+ group with the CNT wall. The Gdm+ group is not as well-hydrated on its flat sides, which binds to the CNT wall. This is consistent with a similar binding of Gdm+ ions to a hydrophobic polymer. In contrast, the Nva residue, which lacks the Gdm+ group, binds to the CNT weakly. We present details of the free energy of binding, molecular structure, and dynamics of these solutes on the CNT surface. Our results highlight the important role of Arg+ residues in protein–CNT or protein-carbon-based material interactions. Such interactions could be manipulated precisely through protein engineering, thereby offering control over protein orientation and structure on CNTs, graphene, or other hydrophobic interfaces." @default.
• W2034750552 created "2016-06-24" @default.
• W2034750552 creator A5003671262 @default.
• W2034750552 creator A5019168059 @default.
• W2034750552 creator A5075239068 @default.
• W2034750552 date "2015-01-28" @default.
• W2034750552 modified "2023-10-03" @default.
• W2034750552 title "Role of Arginine in Mediating Protein–Carbon Nanotube Interactions" @default.
• W2034750552 cites W1967284026 @default.
• W2034750552 cites W1974327005 @default.
• W2034750552 cites W1976721437 @default.
• W2034750552 cites W1980562691 @default.
• W2034750552 cites W1980695842 @default.
• W2034750552 cites W1982388778 @default.
• W2034750552 cites W1982709972 @default.
• W2034750552 cites W1982904490 @default.
• W2034750552 cites W1984542543 @default.
• W2034750552 cites W1984936529 @default.
• W2034750552 cites W1985606233 @default.
• W2034750552 cites W1989856919 @default.
• W2034750552 cites W1992704241 @default.
• W2034750552 cites W1998327691 @default.
• W2034750552 cites W1998353110 @default.
• W2034750552 cites W2001275409 @default.
• W2034750552 cites W2007307122 @default.
• W2034750552 cites W2008682560 @default.
• W2034750552 cites W2009698511 @default.
• W2034750552 cites W2011416230 @default.
• W2034750552 cites W2011971223 @default.
• W2034750552 cites W2019637120 @default.
• W2034750552 cites W2026657651 @default.
• W2034750552 cites W2029667189 @default.
• W2034750552 cites W2031272029 @default.
• W2034750552 cites W2035687084 @default.
• W2034750552 cites W2035723991 @default.
• W2034750552 cites W2036144431 @default.
• W2034750552 cites W2036428801 @default.
• W2034750552 cites W2037839062 @default.
• W2034750552 cites W2039855332 @default.
• W2034750552 cites W2041189078 @default.
• W2034750552 cites W2041638382 @default.
• W2034750552 cites W2046802317 @default.
• W2034750552 cites W2049747350 @default.
• W2034750552 cites W2051710717 @default.
• W2034750552 cites W2059013803 @default.
• W2034750552 cites W2060079863 @default.
• W2034750552 cites W2060996573 @default.
• W2034750552 cites W2062110094 @default.
• W2034750552 cites W2065034701 @default.
• W2034750552 cites W2065802174 @default.
• W2034750552 cites W2066885996 @default.
• W2034750552 cites W2070579594 @default.
• W2034750552 cites W2073623394 @default.
• W2034750552 cites W2076100371 @default.
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• W2034750552 cites W2081110455 @default.
• W2034750552 cites W2081693079 @default.
• W2034750552 cites W2081855562 @default.
• W2034750552 cites W2083794840 @default.
• W2034750552 cites W2092003931 @default.
• W2034750552 cites W2100032560 @default.
• W2034750552 cites W2105120291 @default.
• W2034750552 cites W2107179958 @default.
• W2034750552 cites W2108187138 @default.
• W2034750552 cites W2117814268 @default.
• W2034750552 cites W2118239316 @default.
• W2034750552 cites W2122199548 @default.
• W2034750552 cites W2123952292 @default.
• W2034750552 cites W2131820445 @default.
• W2034750552 cites W2137374477 @default.
• W2034750552 cites W2137433031 @default.
• W2034750552 cites W2138437110 @default.
• W2034750552 cites W2141605195 @default.
• W2034750552 cites W2144288821 @default.
• W2034750552 cites W2149240697 @default.
• W2034750552 cites W2160544821 @default.
• W2034750552 cites W2164370375 @default.
• W2034750552 cites W2321730731 @default.
• W2034750552 cites W2322931248 @default.
• W2034750552 cites W2323128143 @default.
• W2034750552 cites W2324294207 @default.
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• W2034750552 doi "https://doi.org/10.1021/la5043553" @default.
• W2034750552 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25575129" @default.
• W2034750552 hasPublicationYear "2015" @default.
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