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- W2034752713 abstract "Abstract Five week feeding studies with male and female rats ingesting neutralized di-N-butylaminoethanol (DBAE) in water at three dose levels resulted in initial weight loss at the two highest dose levels (males—0.43 and 0.20 gm/kg/day, females— 0.33 and 0.24 gm/kg/day). At the lowest dose level (males—0.13 gm/kg/day, females—0.14 gm/kg/day) no initial weight loss occurred. Following the initial weight loss in the two high dose groups all animals adjusted to the diet and growth rates paralleled those of control animals. At sacrifice, kidney to body weight ratios were elevated in the high dose group although no kidney pathology was evident. Exposure of rats to 70 ppm of DBAE, 6 hours daily for 5 days, resulted in the' death of one of five rats. Five days exposure to 30 ppm of DBAE resulted in growth failure but no mortality. Animals exposed for 6 months to 22 ppm of DBAE were comparable to controls throughout the exposure period." @default.
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- W2034752713 date "1969-01-01" @default.
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- W2034752713 title "Oral and Inhalation Toxicity of 2-N-Dibutylaminoethanol" @default.
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- W2034752713 doi "https://doi.org/10.1080/00028896909343078" @default.
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