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- W2034754118 abstract "There is a growing acceptance of the importance of hypothalamic growth factors in the control of sexual maturation. Basic fibroblast growth factor (bFGF, FGF‐2), a potent mitogen and neurotropic factor for brain cells in vitro , including hypothalamic cells , is widely expressed in the post‐natal CNS but its physiological functions there are largely unknown. Previously, studies of FGF‐2 mRNA regulation in vivo have been hampered by the low levels of FGF‐2 mRNA present in post‐natal tissues. We have applied a sensitive semi‐quantitative procedure based on reverse transcription followed by polymerase chain reaction amplification (RT‐PCR) to detect and estimate relative amounts of mRNAs encoding FGF‐2 and its receptor in the hypothalamic‐hypophyseal axis in individual female rats undergoing sexual maturation." @default.
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- W2034754118 date "1997-02-01" @default.
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- W2034754118 title "Decline in Basic Fibroblast Growth Factor (FGF‐2) mRNA Expression in Female Rat Hypothalamus at Puberty" @default.
- W2034754118 doi "https://doi.org/10.1046/j.1365-2826.1997.00562.x" @default.
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