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- W2034755331 abstract "Chdtogenetic analysis revealed trisomy 20 in 4 desmoid tumors: in 2 cases as the sole aberration, in hd together with +X, -Y and −13 and in I with +8 and a supernumerary marker chromosome. Our findings indicate that gain of chromosome 20 is an early event in the development of a large subset of desmoid tumors and that it is as frequent as +8, the only consistent chromosomal change previously reported in this tumor type. The non-random occurrence of trisomies 8 and 20 in desmoid tumors indicates shared pathogenetic mechanisms with infantile fibrosarcoma, a fibrous tissue tumor characterized by various combinations of trisomies for chromosomes 8, 11, 17 and 20." @default.
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- W2034755331 date "1995-11-15" @default.
- W2034755331 modified "2023-10-13" @default.
- W2034755331 title "Trisomy 20 is a primary chromosome aberration in desmoid tumors" @default.
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- W2034755331 doi "https://doi.org/10.1002/ijc.2910630412" @default.
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