Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034761357> ?p ?o ?g. }
- W2034761357 endingPage "475" @default.
- W2034761357 startingPage "459" @default.
- W2034761357 abstract "The effect of exogenous GM1 ganglioside on selective neurotoxin-induced lesions of serotonin (5-HT) and noradrenaline (NA) neurons in both the central and peripheral nervous systems has been investigated in developing and adult rats and mice by employing neuro- and histochemical techniques. 5,7-Dihydroxytryptamine (5,7-HT) was used to lesion 5-HT neurons, and 6-hydroxydopamine (6-OH-DA) was used to lesion NA neurons. In most lesion models investigated the neurotoxin causes primarily an axonal nerve terminal damage without notably affecting the perikarya. There was no evidence indicating that GM1 interferes with the primary and direct neurodegenerative actions of 5,7-HT or 6-OH-DA on 5-HT and NA nerve terminals, respectively. In all lesion models GM1 had in the chronic stage a counteracting effect on the neurotoxin-induced nerve terminal lesion or enhanced regrowth. The present results are compatible with the view that GM1 has a regrowth-stimulating effect and/or protective actions against secondary retrograde degeneration following the initial nerve terminal lesion induced by the neurotoxin." @default.
- W2034761357 created "2016-06-24" @default.
- W2034761357 creator A5008413693 @default.
- W2034761357 creator A5025520134 @default.
- W2034761357 creator A5028315849 @default.
- W2034761357 creator A5053241457 @default.
- W2034761357 creator A5062457447 @default.
- W2034761357 creator A5072053467 @default.
- W2034761357 creator A5072492077 @default.
- W2034761357 date "1984-01-01" @default.
- W2034761357 modified "2023-10-03" @default.
- W2034761357 title "Effects of GM1 ganglioside on developing and mature serotonin and noradrenaline neurons lesioned by selective neurotoxins" @default.
- W2034761357 cites W1970610557 @default.
- W2034761357 cites W1972731436 @default.
- W2034761357 cites W1978983270 @default.
- W2034761357 cites W1980505845 @default.
- W2034761357 cites W1984178229 @default.
- W2034761357 cites W1989769266 @default.
- W2034761357 cites W1989981999 @default.
- W2034761357 cites W1990276857 @default.
- W2034761357 cites W1996338052 @default.
- W2034761357 cites W1997024999 @default.
- W2034761357 cites W1998397185 @default.
- W2034761357 cites W2001160470 @default.
- W2034761357 cites W2001247903 @default.
- W2034761357 cites W2023743366 @default.
- W2034761357 cites W2028277234 @default.
- W2034761357 cites W2028596158 @default.
- W2034761357 cites W2029874805 @default.
- W2034761357 cites W2041549148 @default.
- W2034761357 cites W2053793791 @default.
- W2034761357 cites W2055962584 @default.
- W2034761357 cites W2064028650 @default.
- W2034761357 cites W2065171993 @default.
- W2034761357 cites W2071577749 @default.
- W2034761357 cites W2072954940 @default.
- W2034761357 cites W2073997713 @default.
- W2034761357 cites W2078156097 @default.
- W2034761357 cites W2082378578 @default.
- W2034761357 cites W2088727446 @default.
- W2034761357 cites W2091316313 @default.
- W2034761357 cites W2092031334 @default.
- W2034761357 cites W2092316899 @default.
- W2034761357 cites W2116801616 @default.
- W2034761357 cites W2163626486 @default.
- W2034761357 cites W2332112968 @default.
- W2034761357 cites W592806300 @default.
- W2034761357 doi "https://doi.org/10.1002/jnr.490120229" @default.
- W2034761357 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6438349" @default.
- W2034761357 hasPublicationYear "1984" @default.
- W2034761357 type Work @default.
- W2034761357 sameAs 2034761357 @default.
- W2034761357 citedByCount "64" @default.
- W2034761357 countsByYear W20347613572013 @default.
- W2034761357 countsByYear W20347613572015 @default.
- W2034761357 countsByYear W20347613572018 @default.
- W2034761357 countsByYear W20347613572019 @default.
- W2034761357 countsByYear W20347613572022 @default.
- W2034761357 crossrefType "journal-article" @default.
- W2034761357 hasAuthorship W2034761357A5008413693 @default.
- W2034761357 hasAuthorship W2034761357A5025520134 @default.
- W2034761357 hasAuthorship W2034761357A5028315849 @default.
- W2034761357 hasAuthorship W2034761357A5053241457 @default.
- W2034761357 hasAuthorship W2034761357A5062457447 @default.
- W2034761357 hasAuthorship W2034761357A5072053467 @default.
- W2034761357 hasAuthorship W2034761357A5072492077 @default.
- W2034761357 hasConcept C126322002 @default.
- W2034761357 hasConcept C134018914 @default.
- W2034761357 hasConcept C142724271 @default.
- W2034761357 hasConcept C169760540 @default.
- W2034761357 hasConcept C170493617 @default.
- W2034761357 hasConcept C185592680 @default.
- W2034761357 hasConcept C2775864247 @default.
- W2034761357 hasConcept C2777331542 @default.
- W2034761357 hasConcept C2779530196 @default.
- W2034761357 hasConcept C2780358027 @default.
- W2034761357 hasConcept C2780997500 @default.
- W2034761357 hasConcept C2781156865 @default.
- W2034761357 hasConcept C37000724 @default.
- W2034761357 hasConcept C529278444 @default.
- W2034761357 hasConcept C55493867 @default.
- W2034761357 hasConcept C71924100 @default.
- W2034761357 hasConcept C86803240 @default.
- W2034761357 hasConceptScore W2034761357C126322002 @default.
- W2034761357 hasConceptScore W2034761357C134018914 @default.
- W2034761357 hasConceptScore W2034761357C142724271 @default.
- W2034761357 hasConceptScore W2034761357C169760540 @default.
- W2034761357 hasConceptScore W2034761357C170493617 @default.
- W2034761357 hasConceptScore W2034761357C185592680 @default.
- W2034761357 hasConceptScore W2034761357C2775864247 @default.
- W2034761357 hasConceptScore W2034761357C2777331542 @default.
- W2034761357 hasConceptScore W2034761357C2779530196 @default.
- W2034761357 hasConceptScore W2034761357C2780358027 @default.
- W2034761357 hasConceptScore W2034761357C2780997500 @default.
- W2034761357 hasConceptScore W2034761357C2781156865 @default.
- W2034761357 hasConceptScore W2034761357C37000724 @default.
- W2034761357 hasConceptScore W2034761357C529278444 @default.
- W2034761357 hasConceptScore W2034761357C55493867 @default.