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• W2034762871 abstract "High affinity capture agents recognizing biomolecular targets are essential in the performance of many proteomic detection methods. Herein, we report the application of a label-free silicon photonic biomolecular analysis platform for simultaneously determining kinetic association and dissociation constants for two representative protein capture agents: a thrombin-binding DNA aptamer and an anti-thrombin monoclonal antibody. The scalability and inherent multiplexing capability of the technology make it an attractive platform for simultaneously evaluating the binding characteristics of multiple capture agents recognizing the same target antigen, and thus a tool complementary to emerging high-throughput capture agent generation strategies." @default.
• W2034762871 created "2016-06-24" @default.
• W2034762871 creator A5001257448 @default.
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• W2034762871 date "2011-01-01" @default.
• W2034762871 modified "2023-10-06" @default.
• W2034762871 title "Multiplexed evaluation of capture agent binding kinetics using arrays of silicon photonic microring resonators" @default.
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• W2034762871 doi "https://doi.org/10.1039/c0an00853b" @default.
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