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- W2034763647 endingPage "R255" @default.
- W2034763647 startingPage "R245" @default.
- W2034763647 abstract "The elegance of animal body plans derives from an intimate connection between function and form, which during organ formation is linked to patterning and growth. Yet, how patterning and growth are coordinated still remains largely a mystery. To study this question the Drosophila wing imaginal disc, an epithelial primordial organ that later forms the adult wing, has proven to be an invaluable and versatile model. Wing disc development is organized around a coordinate system provided by morphogens such as the TGF-β homolog Decapentaplegic (DPP). The function of DPP has been studied at multiple levels: ranging from the kinetics of gradient formation to the establishment and maintenance of target gene domains as well as DPP's role in growth control. Here, we focus on recent publications that both enrich our view of DPP signaling but also highlight outstanding questions of how DPP coordinates patterning and growth during development." @default.
- W2034763647 created "2016-06-24" @default.
- W2034763647 creator A5000177308 @default.
- W2034763647 creator A5012724135 @default.
- W2034763647 creator A5089489482 @default.
- W2034763647 date "2014-03-01" @default.
- W2034763647 modified "2023-10-14" @default.
- W2034763647 title "Coordination of Patterning and Growth by the Morphogen DPP" @default.
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- W2034763647 doi "https://doi.org/10.1016/j.cub.2014.01.055" @default.
- W2034763647 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24650915" @default.
- W2034763647 hasPublicationYear "2014" @default.
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