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• W2034764536 abstract "TransfusionVolume 45, Issue s2 p. 88S-91S Mechanisms of human immunodeficiency virus-1 latency Una O'Doherty, Corresponding Author Una O'Doherty From the Department of Pathology and Laboratory Medicine, Division of Transfusion Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.Una O’Doherty, MD, PhD, Assistant Professor, Department of Pathology and Laboratory Medicine, Division of Transfusion Medicine, University of Pennsylvania, 3620 Hamilton Walk, Philadelphia, PA 19104; e-mail: [email protected].Search for more papers by this author Una O'Doherty, Corresponding Author Una O'Doherty From the Department of Pathology and Laboratory Medicine, Division of Transfusion Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.Una O’Doherty, MD, PhD, Assistant Professor, Department of Pathology and Laboratory Medicine, Division of Transfusion Medicine, University of Pennsylvania, 3620 Hamilton Walk, Philadelphia, PA 19104; e-mail: [email protected].Search for more papers by this author First published: 29 July 2005 https://doi.org/10.1111/j.1537-2995.2005.00538.xCitations: 4Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL REFERENCES 1 Pierson T, McArthur J, Siliciano RF. Reservoirs for HIV-1: mechanisms for viral persistence in the presence of antiviral immune responses and antiretroviral therapy. Annu Rev Immunol 2000; 18: 665- 708. 2 Blankson JN, Persaud D, Siliciano RF. The challenge of viral reservoirs in HIV-1 infection. Annu Rev Med 2002; 53: 557- 93. 3 Stevenson M. HIV-1 pathogenesis. Nat Med 2003; 9: 853- 60. 4 Liu YJ. Dendritic cell subsets and lineages, and their functions in innate and adaptive immunity. Cell 2001; 106: 259- 62. 5 Colonna M, Trinchieri G, Liu YJ. Plasmacytoid dendritic cells in immunity. Nat Immunol 2004; 5: 1219- 26. 6 Banchereau J, Paczesny S, Blanco P, et al. Dendritic cells: controllers of the immune system and a new promise for immunotherapy. Ann N Y Acad Sci 2003; 987: 180- 7. 7 O'Doherty U, Peng M, Gezelter S, et al. Human blood contains two subsets of dendritic cells, one immunologically mature, and the other immature. Immunology 1994; 82: 487- 93. 8 O'Doherty U, Steinman RM, Peng M, et al. Dendritic cells freshly isolated from human blood express CD4 and mature into typical immunostimulatory dendritic cells after culture in monocyte-conditioned medium. J Exp Med 1993; 178: 1067- 78. 9 Lee B, Sharron M, Montaner LJ, Weissman D, Doms RW. Quantification of CD4, CCR5, and CXCR4 levels on lymphocyte subsets, dendritic cells, and differentially conditioned monocyte-derived macrophages. Proc Natl Acad Sci U S A 1999; 96: 5215- 20. 10 Zack JA, Arrigo SJ, Weitsman SR, et al. HIV-1 entry into quiescent primary lymphocytes: molecular analysis reveals a labile, latent viral structure. Cell 1990; 61: 213- 22. 11 Stevenson M, Stanwick TL, Dempsey MP, Lamonica CA. HIV-1 replication is controlled at the level of T cell activation and proviral integration. EMBO J 1990; 9: 1551- 60. 12 Korin YD, Zack JA. Nonproductive human immunodeficiency virus type 1 infection in nucleoside-treated G0 lymphocytes. J Virol 1999; 73: 6526- 32. 13 Ducrey-Rundquist O, Guyader M, Trono D. Modalities of interleukin-7-induced human immunodeficiency virus permissiveness in quiescent T lymphocytes. J Virol 2002; 76: 9103- 11. 14 Chun TW, Carruth L, Finzi D, et al. Quantification of latent tissue reservoirs and total body viral load in HIV-1 infection. Nature 1997; 387: 183- 8. 15 Kutsch O, Benveniste EN, Shaw GM, Levy DN. Direct and quantitative single-cell analysis of human immunodeficiency virus type 1 reactivation from latency. J Virol 2002; 76: 8776- 86. 16 Muto NF, Martinand-Mari C, Adelson ME, Suhadolnik RJ. Inhibition of replication of reactivated human immunodeficiency virus type 1 (HIV-1) in latently infected U1 cells transduced with an HIV-1 long terminal repeat-driven PKR cDNA construct. J Virol 1999; 73: 9021- 8. 17 Jordan A, Bisgrove D, Verdin E. HIV reproducibly establishes a latent infection after acute infection of T cells in vitro. EMBO J 2003; 22: 1868- 77. 18 Swiggard WJ, O'Doherty U, McGain D, Jeyakumar D, Malim MH. Long HIV type 1 reverse transcripts can accumulate stably within resting CD4+ T cells while short ones are degraded. AIDS Res Hum Retroviruses 2004; 20: 285- 95. 19 Weiss A. T-lymphocyte activation. In: WE Paul, editor. Fundamental immunology. Philadelphia: Lippincott Williams & Wilkins Medical; 1998. 20 Dimitrov DS, Willey RL, Sato H, et al. Quantitation of human immunodeficiency virus type 1 infection kinetics. J Virol 1993; 67: 2182- 90. 21 Sato H, Orenstein J, Dimitrov D, Martin M. Cell-to-cell spread of HIV-1 occurs within minutes and may not involve the participation of virus particles. Virology 1992; 186: 712- 24. 22 O'Doherty U, Swiggard WJ, Malim MH. Human immunodeficiency virus type 1 spinoculation enhances infection through virus binding. J Virol 2000; 74: 10074- 80. 23 O'Doherty U, Swiggard WJ, Jeyakumar D, McGain D, Malim MH. A sensitive, quantitative, assay for human immunodeficiency virus type 1 integration. J Virol 2002; 76: 10942- 50. 24 Butler SL, Hansen MST, Bushman FD. A quantitative assay for HIV DNA integration in vivo. Nat Med 2001; 7: 631- 4. 25 Pierson TC, Zhou Y, Kieffer TL, et al. Molecular characterization of preintegration latency in human immunodeficiency virus type 1 infection. J Virol 2002; 76: 8518- 31. 26 Spina CA, Guatelli JC, Richman DD. Establishment of a stable, inducible form of human immunodeficiency virus type 1 DNA in quiescent CD4 lymphocytes in vitro. J Virol 1995; 69: 2877- 988. Citing Literature Volume45, Issues2August 2005Pages 88S-91S ReferencesRelatedInformation" @default.
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