Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034768041> ?p ?o ?g. }
- W2034768041 endingPage "711" @default.
- W2034768041 startingPage "701" @default.
- W2034768041 abstract "BACKGROUND Preoperative embolization of meningiomas is commonly performed to minimize intraoperative bleeding, thereby facilitating surgery and reducing the necessity for transfusion. However, the resulting necrosis and compensatory proliferation reportedly have hampered subsequent histologic grading. METHODS The clinicopathologic features of 64 meningiomas embolized between 1989 and 1997 were assessed. Tumors were graded according to recently published criteria. RESULTS A good embolization result (> 75% reduction in angiographic blush) was achieved in 52%. Histologically, embolized meningiomas showed higher frequencies of necrosis (89%), nuclear atypia (72%), macronucleoli (58%), sheeting (31%), high mitotic index (30%), and brain invasion (14%) when compared with nonembolized counterparts. Median mitotic and MIB-1 indices were slightly elevated (1.5 of 10 high-power fields and 1.6%, respectively). A significant degree of necrosis (> 10%) was found in 43% and was only roughly correlated with extent of angiographic blush reduction or embolization particle size. Histologic grade was benign in 57.8%, atypical in 40.6%, and anaplastic in 1.6%. At last follow-up, there were 13 recurrences, 11 in the atypical/anaplastic (41%) versus 2 in the benign (5%) subsets (P = 0.001). CONCLUSIONS The authors conclude that 1) their grading scheme accurately stratifies embolized meningiomas, 2) extent of necrosis is difficult to predict using standard clinical parameters, and 3) their high incidence of atypical meningioma more likely reflects patient selection biases rather than artifacts induced by the embolization procedure. Cancer 2001;92:701–11. © 2001 American Cancer Society." @default.
- W2034768041 created "2016-06-24" @default.
- W2034768041 creator A5023148778 @default.
- W2034768041 creator A5039685475 @default.
- W2034768041 creator A5052983963 @default.
- W2034768041 creator A5054310342 @default.
- W2034768041 creator A5061678952 @default.
- W2034768041 creator A5063765376 @default.
- W2034768041 date "2001-01-01" @default.
- W2034768041 modified "2023-10-18" @default.
- W2034768041 title "Clinicopathologic assessment and grading of embolized meningiomas" @default.
- W2034768041 cites W145151278 @default.
- W2034768041 cites W1979508054 @default.
- W2034768041 cites W1981743013 @default.
- W2034768041 cites W1992938790 @default.
- W2034768041 cites W1996090880 @default.
- W2034768041 cites W2044355510 @default.
- W2034768041 cites W2049117179 @default.
- W2034768041 cites W2053281003 @default.
- W2034768041 cites W2062336733 @default.
- W2034768041 cites W2067167454 @default.
- W2034768041 cites W2071673294 @default.
- W2034768041 cites W2072585296 @default.
- W2034768041 cites W20731140 @default.
- W2034768041 cites W2088055822 @default.
- W2034768041 cites W2334858962 @default.
- W2034768041 cites W2401889591 @default.
- W2034768041 cites W2406787492 @default.
- W2034768041 doi "https://doi.org/10.1002/1097-0142(20010801)92:3<701::aid-cncr1373>3.0.co;2-7" @default.
- W2034768041 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11505418" @default.
- W2034768041 hasPublicationYear "2001" @default.
- W2034768041 type Work @default.
- W2034768041 sameAs 2034768041 @default.
- W2034768041 citedByCount "45" @default.
- W2034768041 countsByYear W20347680412012 @default.
- W2034768041 countsByYear W20347680412013 @default.
- W2034768041 countsByYear W20347680412014 @default.
- W2034768041 countsByYear W20347680412015 @default.
- W2034768041 countsByYear W20347680412016 @default.
- W2034768041 countsByYear W20347680412017 @default.
- W2034768041 countsByYear W20347680412018 @default.
- W2034768041 countsByYear W20347680412019 @default.
- W2034768041 countsByYear W20347680412020 @default.
- W2034768041 countsByYear W20347680412023 @default.
- W2034768041 crossrefType "journal-article" @default.
- W2034768041 hasAuthorship W2034768041A5023148778 @default.
- W2034768041 hasAuthorship W2034768041A5039685475 @default.
- W2034768041 hasAuthorship W2034768041A5052983963 @default.
- W2034768041 hasAuthorship W2034768041A5054310342 @default.
- W2034768041 hasAuthorship W2034768041A5061678952 @default.
- W2034768041 hasAuthorship W2034768041A5063765376 @default.
- W2034768041 hasBestOaLocation W20347680411 @default.
- W2034768041 hasConcept C126838900 @default.
- W2034768041 hasConcept C127413603 @default.
- W2034768041 hasConcept C142724271 @default.
- W2034768041 hasConcept C147176958 @default.
- W2034768041 hasConcept C204232928 @default.
- W2034768041 hasConcept C2776035437 @default.
- W2034768041 hasConcept C2777286243 @default.
- W2034768041 hasConcept C2779160599 @default.
- W2034768041 hasConcept C2780263296 @default.
- W2034768041 hasConcept C2780387249 @default.
- W2034768041 hasConcept C2781289014 @default.
- W2034768041 hasConcept C503630168 @default.
- W2034768041 hasConcept C509974204 @default.
- W2034768041 hasConcept C66640590 @default.
- W2034768041 hasConcept C71924100 @default.
- W2034768041 hasConcept C86803240 @default.
- W2034768041 hasConcept C93304396 @default.
- W2034768041 hasConcept C95444343 @default.
- W2034768041 hasConceptScore W2034768041C126838900 @default.
- W2034768041 hasConceptScore W2034768041C127413603 @default.
- W2034768041 hasConceptScore W2034768041C142724271 @default.
- W2034768041 hasConceptScore W2034768041C147176958 @default.
- W2034768041 hasConceptScore W2034768041C204232928 @default.
- W2034768041 hasConceptScore W2034768041C2776035437 @default.
- W2034768041 hasConceptScore W2034768041C2777286243 @default.
- W2034768041 hasConceptScore W2034768041C2779160599 @default.
- W2034768041 hasConceptScore W2034768041C2780263296 @default.
- W2034768041 hasConceptScore W2034768041C2780387249 @default.
- W2034768041 hasConceptScore W2034768041C2781289014 @default.
- W2034768041 hasConceptScore W2034768041C503630168 @default.
- W2034768041 hasConceptScore W2034768041C509974204 @default.
- W2034768041 hasConceptScore W2034768041C66640590 @default.
- W2034768041 hasConceptScore W2034768041C71924100 @default.
- W2034768041 hasConceptScore W2034768041C86803240 @default.
- W2034768041 hasConceptScore W2034768041C93304396 @default.
- W2034768041 hasConceptScore W2034768041C95444343 @default.
- W2034768041 hasIssue "3" @default.
- W2034768041 hasLocation W20347680411 @default.
- W2034768041 hasLocation W20347680412 @default.
- W2034768041 hasOpenAccess W2034768041 @default.
- W2034768041 hasPrimaryLocation W20347680411 @default.
- W2034768041 hasRelatedWork W1966317515 @default.
- W2034768041 hasRelatedWork W1971544879 @default.
- W2034768041 hasRelatedWork W2047979053 @default.
- W2034768041 hasRelatedWork W2063583146 @default.
- W2034768041 hasRelatedWork W2415257803 @default.