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- W2034773616 abstract "One of the most challenging transformations in current organic chemistry is the catalytic carboxylation of a C(sp3)–H bond using CO2 gas, an inexpensive and ubiquitous C1 source. A sequential protocol for C(sp3)–H carboxylation by employing a nitrogen-directed, metal-assisted, C–H activation/catalytic silylation reaction in conjunction with fluoride-mediated carboxylation with CO2 was established. The carboxylation proceeded only at the benzylic C(sp3)–Si bond, not at the aromatic C(sp2)–Si, which is advantageous for further manipulations of the products." @default.
- W2034773616 created "2016-06-24" @default.
- W2034773616 creator A5005507976 @default.
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- W2034773616 date "2012-06-19" @default.
- W2034773616 modified "2023-10-02" @default.
- W2034773616 title "Sequential Protocol for C(sp<sup>3</sup>)–H Carboxylation with CO<sub>2</sub>: Transition-Metal-Catalyzed Benzylic C–H Silylation and Fluoride-Mediated Carboxylation" @default.
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- W2034773616 doi "https://doi.org/10.1021/ol301431d" @default.
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