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- W2034776085 abstract "Introduction: Benign prostatic hyperplasia (BPH) is a very common condition in men over 50 years, often resulting in lower urinary tract symptoms (LUTS). Medical therapy aims at improving quality of life and preventing complications. The range of drugs available to treat LUTS is rapidly expanding.Areas covered: Silodosin is a relatively new α1-adrenoreceptor antagonist that is selective for α1A-adrenergic receptor. While causing smooth muscle relaxation in the lower urinary tract, it minimizes blood pressure-related adverse effects. Tadalafil, a PDEs type 5 inhibitor, is a drug recently approved for the treatment of BPH/LUTS that challenges the standard therapy with α1-blockers, especially in men with concomitant erectile dysfunction (ED). Mirabegron is the first β3-adrenoceptor agonist approved for the treatment of symptoms of overactive bladder. BPH-related detrusor overactivity (DO) may be successfully targeted by mirabegron. Gonadotropin-releasing hormone antagonists, intraprostatic injections with NX-1207 and vitamin D3 receptor analogues exerted beneficial effects on LUTS but need further evaluation in clinical studies.Expert opinion: Choosing the right treatment should be guided by patients’ symptoms, comorbidities and potential side effects of available drugs. Silodosin is a valid option for elderly and for people taking antihypertensive drugs. BPH patients affected by ED can target both conditions with continuous tadalafil therapy. The encouraging data on mirabegron use in BPH-DO have to be further assessed in larger prospective randomized clinical trials." @default.
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- W2034776085 date "2014-08-28" @default.
- W2034776085 modified "2023-09-23" @default.
- W2034776085 title "Latest pharmacotherapy options for benign prostatic hyperplasia" @default.
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- W2034776085 cites W1968860914 @default.
- W2034776085 cites W1969317618 @default.
- W2034776085 cites W1969434853 @default.
- W2034776085 cites W1980086110 @default.
- W2034776085 cites W1982562788 @default.
- W2034776085 cites W1986031402 @default.
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- W2034776085 cites W1994414216 @default.
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- W2034776085 doi "https://doi.org/10.1517/14656566.2014.955470" @default.
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