FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034776779> ?p ?o ?g. }

• W2034776779 endingPage "52" @default.
• W2034776779 startingPage "45" @default.
• W2034776779 abstract "Several B-chronic lymphocytic leukemia (B-CLL) clones, represented by different patients can be infected with EBV in vitro. A proportion of the cells becomes activated by the virus, but they rarely yield immortalized cell lines. We used cells from two B-CLL patients which differed in sensitivity to EBV infection. After 7 days in culture, we studied the CLL cells exposed to the B-cell activators Staphylococcus aureus, IL-2 and/or to EBV for expression of the activation markers CD23, CD39 and the adhesion and costimulatory molecules CD54 and CD80, for DNA synthesis, for production of various cytokines and for capacity to stimulate autologous and allogeneic T-lymphocytes. Generally the frequency of cells expressing cytokines in the cytoplasm correlated with the activation status of the populations and with their capacity to stimulate T-cells. It is likely that the difference between the clones with regard to sensitivity to the viral infection, is determined by the maturation state of the CLL cells. It may therefore reflect the variation in the response within a normal B-cell population. The results obtained in the present and in our earlier experiments with EBV provide information concerning the events after primary EBV infection in vivo. The T-lymphocyte stimulatory capacity of the infected CLL cells may be considered as an in vitro correlate to the syndrome of infectious mononucleosis. The detection of cytokines in the infected B-CLL cells suggests that their production by the B-blasts contributes to the level of T-lymphocytosis induced by the primary infection." @default.
• W2034776779 created "2016-06-24" @default.
• W2034776779 creator A5006412648 @default.
• W2034776779 creator A5018768648 @default.
• W2034776779 creator A5032423536 @default.
• W2034776779 creator A5069881022 @default.
• W2034776779 date "1996-12-01" @default.
• W2034776779 modified "2023-10-18" @default.
• W2034776779 title "B-CLL cells experimentally infected with EBV enter DNA synthesis, produce cytokines and stimulate T-lymphocytes" @default.
• W2034776779 cites W1264625845 @default.
• W2034776779 cites W1508213052 @default.
• W2034776779 cites W1572276831 @default.
• W2034776779 cites W1583136467 @default.
• W2034776779 cites W1903461179 @default.
• W2034776779 cites W1970748912 @default.
• W2034776779 cites W1972155218 @default.
• W2034776779 cites W1977355512 @default.
• W2034776779 cites W2004295298 @default.
• W2034776779 cites W2005592215 @default.
• W2034776779 cites W2015012805 @default.
• W2034776779 cites W2023614436 @default.
• W2034776779 cites W2035072676 @default.
• W2034776779 cites W2048319963 @default.
• W2034776779 cites W2053509184 @default.
• W2034776779 cites W2054654563 @default.
• W2034776779 cites W2067858889 @default.
• W2034776779 cites W2076706420 @default.
• W2034776779 cites W2092192751 @default.
• W2034776779 cites W2103504434 @default.
• W2034776779 cites W2161911283 @default.
• W2034776779 cites W2163294735 @default.
• W2034776779 cites W2171477408 @default.
• W2034776779 cites W4313311196 @default.
• W2034776779 doi "https://doi.org/10.1016/s0165-2478(96)02643-0" @default.
• W2034776779 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9030981" @default.
• W2034776779 hasPublicationYear "1996" @default.
• W2034776779 type Work @default.
• W2034776779 sameAs 2034776779 @default.
• W2034776779 citedByCount "8" @default.
• W2034776779 countsByYear W20347767792013 @default.
• W2034776779 crossrefType "journal-article" @default.
• W2034776779 hasAuthorship W2034776779A5006412648 @default.
• W2034776779 hasAuthorship W2034776779A5018768648 @default.
• W2034776779 hasAuthorship W2034776779A5032423536 @default.
• W2034776779 hasAuthorship W2034776779A5069881022 @default.
• W2034776779 hasConcept C10205521 @default.
• W2034776779 hasConcept C141105273 @default.
• W2034776779 hasConcept C154317977 @default.
• W2034776779 hasConcept C159047783 @default.
• W2034776779 hasConcept C159654299 @default.
• W2034776779 hasConcept C159912055 @default.
• W2034776779 hasConcept C202751555 @default.
• W2034776779 hasConcept C203014093 @default.
• W2034776779 hasConcept C2777938653 @default.
• W2034776779 hasConcept C2778297628 @default.
• W2034776779 hasConcept C2778461978 @default.
• W2034776779 hasConcept C28328180 @default.
• W2034776779 hasConcept C2908647359 @default.
• W2034776779 hasConcept C34814297 @default.
• W2034776779 hasConcept C39347974 @default.
• W2034776779 hasConcept C55493867 @default.
• W2034776779 hasConcept C71924100 @default.
• W2034776779 hasConcept C86803240 @default.
• W2034776779 hasConcept C95444343 @default.
• W2034776779 hasConcept C99454951 @default.
• W2034776779 hasConceptScore W2034776779C10205521 @default.
• W2034776779 hasConceptScore W2034776779C141105273 @default.
• W2034776779 hasConceptScore W2034776779C154317977 @default.
• W2034776779 hasConceptScore W2034776779C159047783 @default.
• W2034776779 hasConceptScore W2034776779C159654299 @default.
• W2034776779 hasConceptScore W2034776779C159912055 @default.
• W2034776779 hasConceptScore W2034776779C202751555 @default.
• W2034776779 hasConceptScore W2034776779C203014093 @default.
• W2034776779 hasConceptScore W2034776779C2777938653 @default.
• W2034776779 hasConceptScore W2034776779C2778297628 @default.
• W2034776779 hasConceptScore W2034776779C2778461978 @default.
• W2034776779 hasConceptScore W2034776779C28328180 @default.
• W2034776779 hasConceptScore W2034776779C2908647359 @default.
• W2034776779 hasConceptScore W2034776779C34814297 @default.
• W2034776779 hasConceptScore W2034776779C39347974 @default.
• W2034776779 hasConceptScore W2034776779C55493867 @default.
• W2034776779 hasConceptScore W2034776779C71924100 @default.
• W2034776779 hasConceptScore W2034776779C86803240 @default.
• W2034776779 hasConceptScore W2034776779C95444343 @default.
• W2034776779 hasConceptScore W2034776779C99454951 @default.
• W2034776779 hasIssue "1" @default.
• W2034776779 hasLocation W20347767791 @default.
• W2034776779 hasLocation W20347767792 @default.
• W2034776779 hasOpenAccess W2034776779 @default.
• W2034776779 hasPrimaryLocation W20347767791 @default.
• W2034776779 hasRelatedWork W1857920654 @default.
• W2034776779 hasRelatedWork W1967656246 @default.
• W2034776779 hasRelatedWork W2026268116 @default.
• W2034776779 hasRelatedWork W2031205327 @default.
• W2034776779 hasRelatedWork W2059837242 @default.
• W2034776779 hasRelatedWork W2065111498 @default.
• W2034776779 hasRelatedWork W2094772566 @default.
• W2034776779 hasRelatedWork W2278369333 @default.

• next