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• W2034783371 abstract "The acute regulation of lipolysis in the adipose tissue of ruminants was evaluated with lactating cows (n = 4) and growing ewe lambs (n = 11). Subcutaneous adipose tissue was obtained by biopsy or at slaughter and was incubated with varying concentrations of biologically active insulin-like growth factors-I and -II (IGF-I, IGF-II), somatotropin (ST), prolactin (PRL), or placental lactogen (PL) to determine the effect of these hormones on lipolysis. Complimentary studies were conducted to examine the effects of IGF-I and IGF-II on the acute regulation of lipolysis in adipose tissue from lactating ewes and wethers under a variety of incubation conditions. Isoproterenol (ISO), a beta-adrenergic agonist known to rapidly stimulate lipolysis, was used as a positive control. Incubation with ISO for 3 hr resulted in a significant increase in the rates of lipolysis. However, there was no stimulation of lipolysis over the 3-hr incubation at any concentration or under any conditions for IGF-I or IGF-II. Furthermore, ST, PRL, or PL had no acute effects on the rates of lipolysis in adipose tissue. These data demonstrate that IGF-I, IGF-II, ST, PRL, and PL are not acute effectors of the lipolytic rate in the adipose tissue of ruminants." @default.
• W2034783371 created "2016-06-24" @default.
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• W2034783371 date "1996-05-01" @default.
• W2034783371 modified "2023-10-15" @default.
• W2034783371 title "Insulin-like growth factors-I and -II, somatotropin, prolactin, and placental lactogen are not acute effectors of lipolysis in ruminants" @default.
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• W2034783371 doi "https://doi.org/10.1016/0739-7240(95)00070-4" @default.
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