FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034785558> ?p ?o ?g. }

• W2034785558 abstract "Conditioned taste aversion (CTA) is a form of associative learning in which the pairing of a taste with a toxin causes an animal to avoid the taste. NMDA receptor mediated neurotransmission has been implicated in CTA, but the role of the NMDA receptor glycine-binding site has not been examined. To examine the effects on CTA of the glycinergic NMDA receptor agonist D-cycloserine, rats received D-cycloserine (15 mg/kg, i.p.) or vehicle 15 min before 10-min access to 0.125% saccharin, followed by a low dose of LiCl (19 mg/kg, i.p.). CTA was measured with 24-h, 2-bottle preference tests between water and saccharin. Vehicle-treated rats formed a mild CTA that rapidly extinguished, while d-cycloserine-treated rats formed a stronger CTA that extinguished slowly. The effect of d-cycloserine was specific to the NMDA receptor glycine-binding site, because pretreatment with HA-966 (6 mg/kg), a partial glycinergic agonist, blocked enhancement by D-cycloserine. Three follow-up experiments suggest that the enhancement of CTA was not due to an aversive effect of D-cycloserine. First, saccharin paired with D-cycloserine (15 mg/kg) alone did not induce a CTA, although a higher dose (30 mg/kg) did significantly lower saccharin preference. Second, pretreatment with D-cycloserine did not increase the duration of lying-on-belly behavior induced by LiCl. Third, pretreatment with D-cycloserine did not increase c-Fos induction by either LiCl or vehicle injection in central visceral relays (the nucleus of the solitary tract, the parabrachial nucleus, the central nucleus of the amygdala, the supraoptic nucleus, and the paraventricular nucleus). These results confirm the participation of NMDA receptor, and specifically the glycine-binding site of NMDA receptor, in CTA learning." @default.
• W2034785558 created "2016-06-24" @default.
• W2034785558 creator A5001287527 @default.
• W2034785558 creator A5034908775 @default.
• W2034785558 creator A5043263956 @default.
• W2034785558 creator A5045530452 @default.
• W2034785558 date "2007-08-01" @default.
• W2034785558 modified "2023-10-16" @default.
• W2034785558 title "d-Cycloserine enhances conditioned taste aversion learning in rats" @default.
• W2034785558 cites W1870944445 @default.
• W2034785558 cites W1922090760 @default.
• W2034785558 cites W1946000001 @default.
• W2034785558 cites W1956388268 @default.
• W2034785558 cites W1966550870 @default.
• W2034785558 cites W1978331188 @default.
• W2034785558 cites W1979036236 @default.
• W2034785558 cites W1982732806 @default.
• W2034785558 cites W1982874376 @default.
• W2034785558 cites W1987923616 @default.
• W2034785558 cites W1992432864 @default.
• W2034785558 cites W2001583057 @default.
• W2034785558 cites W2004849995 @default.
• W2034785558 cites W2006280463 @default.
• W2034785558 cites W2007250398 @default.
• W2034785558 cites W2011192707 @default.
• W2034785558 cites W2014304477 @default.
• W2034785558 cites W2019006331 @default.
• W2034785558 cites W2024648639 @default.
• W2034785558 cites W2025902507 @default.
• W2034785558 cites W2026143154 @default.
• W2034785558 cites W2026719952 @default.
• W2034785558 cites W2033667632 @default.
• W2034785558 cites W2037069218 @default.
• W2034785558 cites W2048181000 @default.
• W2034785558 cites W2049075621 @default.
• W2034785558 cites W2054716108 @default.
• W2034785558 cites W2055060782 @default.
• W2034785558 cites W2060788706 @default.
• W2034785558 cites W2062631221 @default.
• W2034785558 cites W2065169750 @default.
• W2034785558 cites W2071984286 @default.
• W2034785558 cites W2073890502 @default.
• W2034785558 cites W2075620728 @default.
• W2034785558 cites W2081678712 @default.
• W2034785558 cites W2082691282 @default.
• W2034785558 cites W2088792824 @default.
• W2034785558 cites W2089465514 @default.
• W2034785558 cites W2093354584 @default.
• W2034785558 cites W2100548110 @default.
• W2034785558 cites W2119453026 @default.
• W2034785558 cites W2121741339 @default.
• W2034785558 cites W2136043560 @default.
• W2034785558 cites W2153584429 @default.
• W2034785558 cites W2156900283 @default.
• W2034785558 cites W2158929612 @default.
• W2034785558 cites W2159446678 @default.
• W2034785558 cites W2412767182 @default.
• W2034785558 cites W28788403 @default.
• W2034785558 cites W2033773987 @default.
• W2034785558 doi "https://doi.org/10.1016/j.pbb.2007.05.006" @default.
• W2034785558 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2756720" @default.
• W2034785558 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17561237" @default.
• W2034785558 hasPublicationYear "2007" @default.
• W2034785558 type Work @default.
• W2034785558 sameAs 2034785558 @default.
• W2034785558 citedByCount "21" @default.
• W2034785558 countsByYear W20347855582012 @default.
• W2034785558 countsByYear W20347855582013 @default.
• W2034785558 countsByYear W20347855582014 @default.
• W2034785558 countsByYear W20347855582018 @default.
• W2034785558 countsByYear W20347855582019 @default.
• W2034785558 crossrefType "journal-article" @default.
• W2034785558 hasAuthorship W2034785558A5001287527 @default.
• W2034785558 hasAuthorship W2034785558A5034908775 @default.
• W2034785558 hasAuthorship W2034785558A5043263956 @default.
• W2034785558 hasAuthorship W2034785558A5045530452 @default.
• W2034785558 hasBestOaLocation W20347855582 @default.
• W2034785558 hasConcept C126322002 @default.
• W2034785558 hasConcept C134018914 @default.
• W2034785558 hasConcept C15744967 @default.
• W2034785558 hasConcept C164742699 @default.
• W2034785558 hasConcept C170493617 @default.
• W2034785558 hasConcept C185592680 @default.
• W2034785558 hasConcept C2778938600 @default.
• W2034785558 hasConcept C2779147919 @default.
• W2034785558 hasConcept C2781122200 @default.
• W2034785558 hasConcept C42219234 @default.
• W2034785558 hasConcept C501593827 @default.
• W2034785558 hasConcept C55493867 @default.
• W2034785558 hasConcept C67018056 @default.
• W2034785558 hasConcept C71924100 @default.
• W2034785558 hasConcept C8868529 @default.
• W2034785558 hasConcept C98274493 @default.
• W2034785558 hasConceptScore W2034785558C126322002 @default.
• W2034785558 hasConceptScore W2034785558C134018914 @default.
• W2034785558 hasConceptScore W2034785558C15744967 @default.
• W2034785558 hasConceptScore W2034785558C164742699 @default.
• W2034785558 hasConceptScore W2034785558C170493617 @default.
• W2034785558 hasConceptScore W2034785558C185592680 @default.
• W2034785558 hasConceptScore W2034785558C2778938600 @default.

• next