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- W2034786724 abstract "Biofilms are complex aggregations of microbes formed at interfaces, and once established can be difficult to eradicate. Often, biofilms come into contact with clean surfaces and transfer cells causing contamination. We use the atomic force microscope (AFM) to study the effects of contact time on the adhesive interactions between an established biofilm and clean surfaces. AFM cantilevers are modified with living, Gram-negative bacteria biofilms, allowing us to leave the biofilm in prolonged contact with a substrate. As the cantilever retracts from the surface, we monitor the energy required to overcome the adhesion between the bacteria and substrate. Generally, increased contact time leads to stronger adhesion due to bond strengthening. However, the magnitude of this effect varies greatly among substrates with different surface potentials and hydrophobic properties." @default.
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- W2034786724 date "2012-01-01" @default.
- W2034786724 modified "2023-09-29" @default.
- W2034786724 title "The Effects of Contact Time on the Adhesive Properties of an Established Bacterial Biofilm" @default.
- W2034786724 doi "https://doi.org/10.1016/j.bpj.2011.11.3202" @default.
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