Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034793166> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2034793166 endingPage "885" @default.
- W2034793166 startingPage "879" @default.
- W2034793166 abstract "Intraplantar injection of canatoxin (CNTX) induced a dose-dependent rat hind-paw edema which was distinguished by two phases. In the first phase, observed between 0 and 2 hr after CNTX injection, there was an increase in paw volume, with no apparent involvement of inflammatory phagocytic cells. The second phase, beginning at about the 3rd hr, was characterized by an intense cellular infiltration at the site of administration which was coincident with a further increase in paw swelling. The edema was maximum at 6 hr after injection and disappeared within 48 hr at doses of 50–100 μg, while at doses of 200–300 μg edema was present in excess of 48 hr. The pharmacological studies suggested that CNTX-induced edema is a multi-mediated phenomenon. Histamine, serotonin, PAF and prostaglandins are likely involved in the first phase. Lipoxygenase metabolites, probably leukotrienes, seem to play a major role in the second phase, and may account for the development of cellular infiltration in the inflammatory site." @default.
- W2034793166 created "2016-06-24" @default.
- W2034793166 creator A5000167265 @default.
- W2034793166 creator A5020738891 @default.
- W2034793166 creator A5022145074 @default.
- W2034793166 date "1992-08-01" @default.
- W2034793166 modified "2023-10-04" @default.
- W2034793166 title "Pharmacological characterization of rat paw edema induced by canatoxin, the toxic protein from Canavalia ensiformis (jack bean) seeds" @default.
- W2034793166 cites W1931089900 @default.
- W2034793166 cites W1965727190 @default.
- W2034793166 cites W1977617171 @default.
- W2034793166 cites W2050908838 @default.
- W2034793166 cites W2051972752 @default.
- W2034793166 cites W2058145004 @default.
- W2034793166 cites W2072626696 @default.
- W2034793166 cites W2078167757 @default.
- W2034793166 cites W2084827879 @default.
- W2034793166 cites W4232508541 @default.
- W2034793166 cites W4236717668 @default.
- W2034793166 doi "https://doi.org/10.1016/0041-0101(92)90386-j" @default.
- W2034793166 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1523679" @default.
- W2034793166 hasPublicationYear "1992" @default.
- W2034793166 type Work @default.
- W2034793166 sameAs 2034793166 @default.
- W2034793166 citedByCount "20" @default.
- W2034793166 countsByYear W20347931662013 @default.
- W2034793166 countsByYear W20347931662014 @default.
- W2034793166 countsByYear W20347931662015 @default.
- W2034793166 countsByYear W20347931662016 @default.
- W2034793166 countsByYear W20347931662017 @default.
- W2034793166 countsByYear W20347931662018 @default.
- W2034793166 countsByYear W20347931662021 @default.
- W2034793166 countsByYear W20347931662023 @default.
- W2034793166 crossrefType "journal-article" @default.
- W2034793166 hasAuthorship W2034793166A5000167265 @default.
- W2034793166 hasAuthorship W2034793166A5020738891 @default.
- W2034793166 hasAuthorship W2034793166A5022145074 @default.
- W2034793166 hasConcept C1122143 @default.
- W2034793166 hasConcept C121332964 @default.
- W2034793166 hasConcept C126322002 @default.
- W2034793166 hasConcept C134018914 @default.
- W2034793166 hasConcept C142724271 @default.
- W2034793166 hasConcept C153400128 @default.
- W2034793166 hasConcept C170493617 @default.
- W2034793166 hasConcept C181199279 @default.
- W2034793166 hasConcept C185592680 @default.
- W2034793166 hasConcept C2775864247 @default.
- W2034793166 hasConcept C2778540859 @default.
- W2034793166 hasConcept C2780857362 @default.
- W2034793166 hasConcept C2780886150 @default.
- W2034793166 hasConcept C2781227287 @default.
- W2034793166 hasConcept C55493867 @default.
- W2034793166 hasConcept C71924100 @default.
- W2034793166 hasConcept C97355855 @default.
- W2034793166 hasConcept C98274493 @default.
- W2034793166 hasConceptScore W2034793166C1122143 @default.
- W2034793166 hasConceptScore W2034793166C121332964 @default.
- W2034793166 hasConceptScore W2034793166C126322002 @default.
- W2034793166 hasConceptScore W2034793166C134018914 @default.
- W2034793166 hasConceptScore W2034793166C142724271 @default.
- W2034793166 hasConceptScore W2034793166C153400128 @default.
- W2034793166 hasConceptScore W2034793166C170493617 @default.
- W2034793166 hasConceptScore W2034793166C181199279 @default.
- W2034793166 hasConceptScore W2034793166C185592680 @default.
- W2034793166 hasConceptScore W2034793166C2775864247 @default.
- W2034793166 hasConceptScore W2034793166C2778540859 @default.
- W2034793166 hasConceptScore W2034793166C2780857362 @default.
- W2034793166 hasConceptScore W2034793166C2780886150 @default.
- W2034793166 hasConceptScore W2034793166C2781227287 @default.
- W2034793166 hasConceptScore W2034793166C55493867 @default.
- W2034793166 hasConceptScore W2034793166C71924100 @default.
- W2034793166 hasConceptScore W2034793166C97355855 @default.
- W2034793166 hasConceptScore W2034793166C98274493 @default.
- W2034793166 hasIssue "8" @default.
- W2034793166 hasLocation W20347931661 @default.
- W2034793166 hasLocation W20347931662 @default.
- W2034793166 hasOpenAccess W2034793166 @default.
- W2034793166 hasPrimaryLocation W20347931661 @default.
- W2034793166 hasRelatedWork W1522849455 @default.
- W2034793166 hasRelatedWork W1965692775 @default.
- W2034793166 hasRelatedWork W1971453675 @default.
- W2034793166 hasRelatedWork W1983315707 @default.
- W2034793166 hasRelatedWork W2027622212 @default.
- W2034793166 hasRelatedWork W2050824222 @default.
- W2034793166 hasRelatedWork W2055572014 @default.
- W2034793166 hasRelatedWork W2128286595 @default.
- W2034793166 hasRelatedWork W2172131010 @default.
- W2034793166 hasRelatedWork W4241062279 @default.
- W2034793166 hasVolume "30" @default.
- W2034793166 isParatext "false" @default.
- W2034793166 isRetracted "false" @default.
- W2034793166 magId "2034793166" @default.
- W2034793166 workType "article" @default.