FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034794380> ?p ?o ?g. }

• W2034794380 endingPage "2940" @default.
• W2034794380 startingPage "2933" @default.
• W2034794380 abstract "The Assessing Worldwide Antimicrobial Resistance Evaluation (AWARE) surveillance program is a sentinel resistance monitoring system designed to track the activity of ceftaroline and comparator agents. In the United States, a total of 8,434 isolates were collected during the 2010 surveillance program from 65 medical centers distributed across the nine census regions (5 to 10 medical centers per region). All organisms were isolated from documented infections, including 3,055 (36.2%) bloodstream infections, 2,282 (27.1%) respiratory tract infections, 1,965 (23.3%) acute bacterial skin and skin structure infections, 665 (7.9%) urinary tract infections, and 467 (5.5%) miscellaneous other infection sites. Ceftaroline was the most potent β-lactam agent tested against staphylococci. The MIC(90) values were 1 μg/ml for methicillin-resistant Staphylococcus aureus (MRSA; 98.4% susceptible) and 0.5 μg/ml for methicillin-resistant coagulase-negative staphylococci (CoNS). Ceftaroline was 16- to 32-fold more potent than ceftriaxone against methicillin-susceptible staphylococcal strains. All staphylococcus isolates (S. aureus and CoNS) were inhibited at ceftaroline MIC values of ≤ 2 μg/ml. Ceftaroline also displayed potent activity against streptococci (MIC(90), 0.015 μg/ml for beta-hemolytic streptococci; MIC(90), 0.25 μg/ml for penicillin-resistant Streptococcus pneumoniae). Potent activity was also shown against Gram-negative pathogens (Haemophilus influenzae, Haemophilus parainfluenzae, and Moraxella catarrhalis). Furthermore, wild-type strains of Enterobacteriaceae (non-extended-spectrum β-lactamase [ESBL]-producing strains and non-AmpC-hyperproducing strains) were often susceptible to ceftaroline. Continued monitoring through surveillance networks will allow for the assessment of the evolution of resistance as this new cephalosporin is used more broadly to provide clinicians with up-to-date information to assist in antibiotic stewardship and therapeutic decision making." @default.
• W2034794380 created "2016-06-24" @default.
• W2034794380 creator A5006715126 @default.
• W2034794380 creator A5008542312 @default.
• W2034794380 creator A5037843249 @default.
• W2034794380 creator A5044679653 @default.
• W2034794380 date "2012-06-01" @default.
• W2034794380 modified "2023-10-12" @default.
• W2034794380 title "Summary of Ceftaroline Activity against Pathogens in the United States, 2010: Report from the Assessing Worldwide Antimicrobial Resistance Evaluation (AWARE) Surveillance Program" @default.
• W2034794380 cites W2004627090 @default.
• W2034794380 cites W2007258575 @default.
• W2034794380 cites W2011376880 @default.
• W2034794380 cites W2015652530 @default.
• W2034794380 cites W2029733998 @default.
• W2034794380 cites W2069153240 @default.
• W2034794380 cites W2073090965 @default.
• W2034794380 cites W2104894994 @default.
• W2034794380 cites W2107017863 @default.
• W2034794380 cites W2115486016 @default.
• W2034794380 cites W2123677996 @default.
• W2034794380 cites W2125893214 @default.
• W2034794380 cites W2139831974 @default.
• W2034794380 cites W2144012207 @default.
• W2034794380 cites W2149500566 @default.
• W2034794380 cites W2149940840 @default.
• W2034794380 cites W2151880722 @default.
• W2034794380 cites W2156888060 @default.
• W2034794380 cites W2329831612 @default.
• W2034794380 cites W2916433178 @default.
• W2034794380 cites W4237533259 @default.
• W2034794380 doi "https://doi.org/10.1128/aac.00330-12" @default.
• W2034794380 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3370782" @default.
• W2034794380 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22470115" @default.
• W2034794380 hasPublicationYear "2012" @default.
• W2034794380 type Work @default.
• W2034794380 sameAs 2034794380 @default.
• W2034794380 citedByCount "67" @default.
• W2034794380 countsByYear W20347943802012 @default.
• W2034794380 countsByYear W20347943802013 @default.
• W2034794380 countsByYear W20347943802014 @default.
• W2034794380 countsByYear W20347943802015 @default.
• W2034794380 countsByYear W20347943802016 @default.
• W2034794380 countsByYear W20347943802017 @default.
• W2034794380 countsByYear W20347943802018 @default.
• W2034794380 countsByYear W20347943802019 @default.
• W2034794380 countsByYear W20347943802020 @default.
• W2034794380 countsByYear W20347943802022 @default.
• W2034794380 countsByYear W20347943802023 @default.
• W2034794380 crossrefType "journal-article" @default.
• W2034794380 hasAuthorship W2034794380A5006715126 @default.
• W2034794380 hasAuthorship W2034794380A5008542312 @default.
• W2034794380 hasAuthorship W2034794380A5037843249 @default.
• W2034794380 hasAuthorship W2034794380A5044679653 @default.
• W2034794380 hasBestOaLocation W20347943801 @default.
• W2034794380 hasConcept C126322002 @default.
• W2034794380 hasConcept C174802600 @default.
• W2034794380 hasConcept C2776012195 @default.
• W2034794380 hasConcept C2776551000 @default.
• W2034794380 hasConcept C2776925733 @default.
• W2034794380 hasConcept C2777033495 @default.
• W2034794380 hasConcept C2777052132 @default.
• W2034794380 hasConcept C2779489039 @default.
• W2034794380 hasConcept C2781253189 @default.
• W2034794380 hasConcept C4937899 @default.
• W2034794380 hasConcept C501593827 @default.
• W2034794380 hasConcept C523546767 @default.
• W2034794380 hasConcept C534529494 @default.
• W2034794380 hasConcept C54355233 @default.
• W2034794380 hasConcept C64778159 @default.
• W2034794380 hasConcept C71924100 @default.
• W2034794380 hasConcept C86803240 @default.
• W2034794380 hasConcept C89423630 @default.
• W2034794380 hasConcept C94665300 @default.
• W2034794380 hasConceptScore W2034794380C126322002 @default.
• W2034794380 hasConceptScore W2034794380C174802600 @default.
• W2034794380 hasConceptScore W2034794380C2776012195 @default.
• W2034794380 hasConceptScore W2034794380C2776551000 @default.
• W2034794380 hasConceptScore W2034794380C2776925733 @default.
• W2034794380 hasConceptScore W2034794380C2777033495 @default.
• W2034794380 hasConceptScore W2034794380C2777052132 @default.
• W2034794380 hasConceptScore W2034794380C2779489039 @default.
• W2034794380 hasConceptScore W2034794380C2781253189 @default.
• W2034794380 hasConceptScore W2034794380C4937899 @default.
• W2034794380 hasConceptScore W2034794380C501593827 @default.
• W2034794380 hasConceptScore W2034794380C523546767 @default.
• W2034794380 hasConceptScore W2034794380C534529494 @default.
• W2034794380 hasConceptScore W2034794380C54355233 @default.
• W2034794380 hasConceptScore W2034794380C64778159 @default.
• W2034794380 hasConceptScore W2034794380C71924100 @default.
• W2034794380 hasConceptScore W2034794380C86803240 @default.
• W2034794380 hasConceptScore W2034794380C89423630 @default.
• W2034794380 hasConceptScore W2034794380C94665300 @default.
• W2034794380 hasIssue "6" @default.
• W2034794380 hasLocation W20347943801 @default.
• W2034794380 hasLocation W20347943802 @default.
• W2034794380 hasLocation W20347943803 @default.
• W2034794380 hasLocation W20347943804 @default.
• W2034794380 hasOpenAccess W2034794380 @default.

• next