FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034794958> ?p ?o ?g. }

• W2034794958 endingPage "153" @default.
• W2034794958 startingPage "147" @default.
• W2034794958 abstract "Psoriasis is an autoimmune disease mediated mainly by dysfunctional peripheral blood T cells. Both CD4+/CD8+ T cells and CD4+CD25+ regulatory T cells derived from psoriatic CD34+ bone marrow cells in vitro have been found to be functionally similar to those psoriatic circulating and lesional T cells. Notch signaling participates in diverse cell fate decisions during T cell development and has been reported to influence the proliferation of hematopoietic stem cells and the differentiation of T cells. The purpose of this study was to investigate the expression levels of Notch receptor 1, 2 and its target gene Hes-1 in CD34+ cells from patients with psoriasis. The total RNA and protein of CD34+ cells were extracted, and the mRNA as well as protein expression of Notch1, Notch2 and Hes-1 were investigated using real-time PCR and Western blot assays. We found that the mRNA and protein expression levels of Notch1 and Hes-1 in psoriasis patients were higher compared to normal controls, while the Notch2 mRNA and protein expression levels in psoriasis patients were similar to those of normal controls. The elevated Notch1 and Hes-1 expression levels in psoriatic CD34+ cells might be one reason for the immune disorders which are mainly mediated by T cells." @default.
• W2034794958 created "2016-06-24" @default.
• W2034794958 creator A5011029233 @default.
• W2034794958 creator A5017947172 @default.
• W2034794958 creator A5065625415 @default.
• W2034794958 creator A5069461912 @default.
• W2034794958 creator A5076202570 @default.
• W2034794958 creator A5090193534 @default.
• W2034794958 date "2012-01-01" @default.
• W2034794958 modified "2023-10-16" @default.
• W2034794958 title "Expression of Notch Receptor and Its Target Gene Hes-1 in Bone Marrow CD34+ Cells from Patients with Psoriasis" @default.
• W2034794958 cites W1502695618 @default.
• W2034794958 cites W1506552782 @default.
• W2034794958 cites W1980212327 @default.
• W2034794958 cites W1997299625 @default.
• W2034794958 cites W2003002694 @default.
• W2034794958 cites W2017251211 @default.
• W2034794958 cites W2043279623 @default.
• W2034794958 cites W2046928493 @default.
• W2034794958 cites W2051433490 @default.
• W2034794958 cites W2067131315 @default.
• W2034794958 cites W2094740058 @default.
• W2034794958 cites W2095397411 @default.
• W2034794958 cites W2096015304 @default.
• W2034794958 cites W2107277218 @default.
• W2034794958 cites W2110483286 @default.
• W2034794958 cites W2129016683 @default.
• W2034794958 cites W2150792914 @default.
• W2034794958 cites W2404234352 @default.
• W2034794958 cites W4230605418 @default.
• W2034794958 cites W8143991 @default.
• W2034794958 cites W82909710 @default.
• W2034794958 doi "https://doi.org/10.1159/000342359" @default.
• W2034794958 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23037857" @default.
• W2034794958 hasPublicationYear "2012" @default.
• W2034794958 type Work @default.
• W2034794958 sameAs 2034794958 @default.
• W2034794958 citedByCount "7" @default.
• W2034794958 countsByYear W20347949582015 @default.
• W2034794958 countsByYear W20347949582017 @default.
• W2034794958 countsByYear W20347949582018 @default.
• W2034794958 countsByYear W20347949582022 @default.
• W2034794958 crossrefType "journal-article" @default.
• W2034794958 hasAuthorship W2034794958A5011029233 @default.
• W2034794958 hasAuthorship W2034794958A5017947172 @default.
• W2034794958 hasAuthorship W2034794958A5065625415 @default.
• W2034794958 hasAuthorship W2034794958A5069461912 @default.
• W2034794958 hasAuthorship W2034794958A5076202570 @default.
• W2034794958 hasAuthorship W2034794958A5090193534 @default.
• W2034794958 hasConcept C10205521 @default.
• W2034794958 hasConcept C109159458 @default.
• W2034794958 hasConcept C153911025 @default.
• W2034794958 hasConcept C161879069 @default.
• W2034794958 hasConcept C167672396 @default.
• W2034794958 hasConcept C203014093 @default.
• W2034794958 hasConcept C2776090121 @default.
• W2034794958 hasConcept C2780007613 @default.
• W2034794958 hasConcept C2780564577 @default.
• W2034794958 hasConcept C28328180 @default.
• W2034794958 hasConcept C502942594 @default.
• W2034794958 hasConcept C62478195 @default.
• W2034794958 hasConcept C79484868 @default.
• W2034794958 hasConcept C86803240 @default.
• W2034794958 hasConcept C8891405 @default.
• W2034794958 hasConcept C95444343 @default.
• W2034794958 hasConceptScore W2034794958C10205521 @default.
• W2034794958 hasConceptScore W2034794958C109159458 @default.
• W2034794958 hasConceptScore W2034794958C153911025 @default.
• W2034794958 hasConceptScore W2034794958C161879069 @default.
• W2034794958 hasConceptScore W2034794958C167672396 @default.
• W2034794958 hasConceptScore W2034794958C203014093 @default.
• W2034794958 hasConceptScore W2034794958C2776090121 @default.
• W2034794958 hasConceptScore W2034794958C2780007613 @default.
• W2034794958 hasConceptScore W2034794958C2780564577 @default.
• W2034794958 hasConceptScore W2034794958C28328180 @default.
• W2034794958 hasConceptScore W2034794958C502942594 @default.
• W2034794958 hasConceptScore W2034794958C62478195 @default.
• W2034794958 hasConceptScore W2034794958C79484868 @default.
• W2034794958 hasConceptScore W2034794958C86803240 @default.
• W2034794958 hasConceptScore W2034794958C8891405 @default.
• W2034794958 hasConceptScore W2034794958C95444343 @default.
• W2034794958 hasIssue "2" @default.
• W2034794958 hasLocation W20347949581 @default.
• W2034794958 hasLocation W20347949582 @default.
• W2034794958 hasOpenAccess W2034794958 @default.
• W2034794958 hasPrimaryLocation W20347949581 @default.
• W2034794958 hasRelatedWork W1595064677 @default.
• W2034794958 hasRelatedWork W1978598034 @default.
• W2034794958 hasRelatedWork W2027844516 @default.
• W2034794958 hasRelatedWork W2097466377 @default.
• W2034794958 hasRelatedWork W2119511363 @default.
• W2034794958 hasRelatedWork W2146860878 @default.
• W2034794958 hasRelatedWork W2253242983 @default.
• W2034794958 hasRelatedWork W2416649916 @default.
• W2034794958 hasRelatedWork W2983614160 @default.
• W2034794958 hasRelatedWork W3032207719 @default.
• W2034794958 hasVolume "225" @default.
• W2034794958 isParatext "false" @default.

• next