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- W2034797501 abstract "The mathematical product of dose and relative biological effectiveness (DR) is commonly used empirically as the 'effective' dose of radiations. It is shown that such a physical interpretation of DR would be both mathematically and logically inconsistent unless the action of each radiation has a constant RBE value for all end-effects. This is contrary to general experimental findings. Based on the isoeffect biological connotation in the definition of RBE, a biophysical interpretation is introduced in which DR is always interpreted with respect to a particular end-effect on which the RBE value is evaluated, somewhat similar to having an extra biological dimension. Hence, only DRs evaluated for the same end-effect can be meaningfully computed together in a mixture. From the empirical results of radiobiological experiments using mixtures of radiations of different qualities, DRs of radiation components are shown to be additive in a mixture just like physical doses." @default.
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- W2034797501 date "1990-04-01" @default.
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- W2034797501 title "On the biophysical interpretation of the mathematical product of dose and relative biological effectiveness" @default.
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- W2034797501 doi "https://doi.org/10.1088/0031-9155/35/4/001" @default.
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