FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034803567> ?p ?o ?g. }

• W2034803567 endingPage "1119" @default.
• W2034803567 startingPage "1109" @default.
• W2034803567 abstract "σB is an alternative σ factor that regulates stress response and virulence genes in the foodborne pathogen Listeria monocytogenes. To gain further insight into σB-dependent regulatory mechanisms in L. monocytogenes, we (i) performed quantitative proteomic comparisons between the L. monocytogenes parent strain 10403S and an isogenic ΔsigB mutant and (ii) conducted a meta-analysis of published microarray studies on the 10403S σB regulon. A total of 134 genes were found to be significantly positively regulated by σB at the transcriptomic level with >75 % of these genes preceded by putative σB-dependent promoters; 21 of these 134 genes were also found to be positively regulated by σB through proteomics. In addition, 15 proteins were only found to be positively regulated by σB through proteomics analyses, including Lmo1349, a putative glycine cleavage system protein. The lmo1349 gene is preceded by a 5′ UTR that functions as a glycine riboswitch, which suggests regulation of glycine metabolism by σB in L. monocytogenes. Herein, we propose a model where σB upregulates pathways that facilitate biosynthesis and uptake of glycine, which may then activate this riboswitch. Our data also (i) identified a number of σB-dependent proteins that appear to be encoded by genes that are co-regulated by multiple transcriptional regulators, in particular PrfA, and (ii) found σB-dependent genes and proteins to be overrepresented in the ‘energy metabolism’ role category, highlighting contributions of the σB regulon to L. monocytogenes energy metabolism as well as a role of PrfA and σB interaction in regulating aspects of energy metabolism in L. monocytogenes." @default.
• W2034803567 created "2016-06-24" @default.
• W2034803567 creator A5011967453 @default.
• W2034803567 creator A5033699998 @default.
• W2034803567 creator A5035099420 @default.
• W2034803567 creator A5045991055 @default.
• W2034803567 creator A5082217142 @default.
• W2034803567 date "2013-06-01" @default.
• W2034803567 modified "2023-10-16" @default.
• W2034803567 title "Refinement of the Listeria monocytogenes σB regulon through quantitative proteomic analysis" @default.
• W2034803567 cites W1527017806 @default.
• W2034803567 cites W1559269196 @default.
• W2034803567 cites W1958958319 @default.
• W2034803567 cites W1965779535 @default.
• W2034803567 cites W1985810589 @default.
• W2034803567 cites W1996535143 @default.
• W2034803567 cites W2000133076 @default.
• W2034803567 cites W2001271146 @default.
• W2034803567 cites W2008362312 @default.
• W2034803567 cites W2008883486 @default.
• W2034803567 cites W2017408489 @default.
• W2034803567 cites W2037780227 @default.
• W2034803567 cites W2049105226 @default.
• W2034803567 cites W2058486042 @default.
• W2034803567 cites W2062555424 @default.
• W2034803567 cites W2075624885 @default.
• W2034803567 cites W2078739770 @default.
• W2034803567 cites W2099014049 @default.
• W2034803567 cites W2103056313 @default.
• W2034803567 cites W2103326203 @default.
• W2034803567 cites W2109295007 @default.
• W2034803567 cites W2111897930 @default.
• W2034803567 cites W2112761948 @default.
• W2034803567 cites W2114286698 @default.
• W2034803567 cites W2115919477 @default.
• W2034803567 cites W2124056179 @default.
• W2034803567 cites W2129793572 @default.
• W2034803567 cites W2138080389 @default.
• W2034803567 cites W2142411084 @default.
• W2034803567 cites W2146995820 @default.
• W2034803567 cites W2147681005 @default.
• W2034803567 cites W2150462933 @default.
• W2034803567 cites W2152205844 @default.
• W2034803567 cites W2152453854 @default.
• W2034803567 cites W2160500822 @default.
• W2034803567 cites W2162376398 @default.
• W2034803567 cites W2164551795 @default.
• W2034803567 cites W2169889511 @default.
• W2034803567 cites W2170906273 @default.
• W2034803567 cites W2171214502 @default.
• W2034803567 cites W2171918702 @default.
• W2034803567 doi "https://doi.org/10.1099/mic.0.066001-0" @default.
• W2034803567 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3709693" @default.
• W2034803567 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23618998" @default.
• W2034803567 hasPublicationYear "2013" @default.
• W2034803567 type Work @default.
• W2034803567 sameAs 2034803567 @default.
• W2034803567 citedByCount "26" @default.
• W2034803567 countsByYear W20348035672014 @default.
• W2034803567 countsByYear W20348035672015 @default.
• W2034803567 countsByYear W20348035672016 @default.
• W2034803567 countsByYear W20348035672017 @default.
• W2034803567 countsByYear W20348035672018 @default.
• W2034803567 countsByYear W20348035672019 @default.
• W2034803567 countsByYear W20348035672020 @default.
• W2034803567 countsByYear W20348035672021 @default.
• W2034803567 countsByYear W20348035672022 @default.
• W2034803567 crossrefType "journal-article" @default.
• W2034803567 hasAuthorship W2034803567A5011967453 @default.
• W2034803567 hasAuthorship W2034803567A5033699998 @default.
• W2034803567 hasAuthorship W2034803567A5035099420 @default.
• W2034803567 hasAuthorship W2034803567A5045991055 @default.
• W2034803567 hasAuthorship W2034803567A5082217142 @default.
• W2034803567 hasBestOaLocation W20348035672 @default.
• W2034803567 hasConcept C101762097 @default.
• W2034803567 hasConcept C104317684 @default.
• W2034803567 hasConcept C143065580 @default.
• W2034803567 hasConcept C148625055 @default.
• W2034803567 hasConcept C150194340 @default.
• W2034803567 hasConcept C160560785 @default.
• W2034803567 hasConcept C162317418 @default.
• W2034803567 hasConcept C194993378 @default.
• W2034803567 hasConcept C2777756961 @default.
• W2034803567 hasConcept C2781350384 @default.
• W2034803567 hasConcept C46111723 @default.
• W2034803567 hasConcept C47319516 @default.
• W2034803567 hasConcept C515207424 @default.
• W2034803567 hasConcept C523546767 @default.
• W2034803567 hasConcept C54355233 @default.
• W2034803567 hasConcept C62361671 @default.
• W2034803567 hasConcept C67705224 @default.
• W2034803567 hasConcept C8415881 @default.
• W2034803567 hasConcept C86803240 @default.
• W2034803567 hasConcept C89423630 @default.
• W2034803567 hasConceptScore W2034803567C101762097 @default.
• W2034803567 hasConceptScore W2034803567C104317684 @default.
• W2034803567 hasConceptScore W2034803567C143065580 @default.
• W2034803567 hasConceptScore W2034803567C148625055 @default.

• next