FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034807185> ?p ?o ?g. }

• W2034807185 endingPage "790" @default.
• W2034807185 startingPage "778" @default.
• W2034807185 abstract "Within the field of dental tissue engineering, the establishment of adequate tissue vascularization is one of the most important burdens to overcome. As vascular access within the tooth is restricted by the apical foramen, it is of major importance to implement effective vascularization strategies in order to recreate viable components of teeth and periodontal tissues. However, while the current regenerative approaches focus on the use of dental stem cells (DSCs), little is known about these cells and their ability to promote angiogenesis. Therefore, the present study aimed to elucidate the paracrine angiogenic properties of postnatal DSCs, in particular dental pulp stem cells (DPSCs), stem cells from the apical papilla (SCAPs) and dental follicle precursor cells (FSCs). An antibody array, together with RT-PCR and ELISA, pointed out the differential expression of pro-angiogenic as well as anti-angiogenic factors by cultured DSCs and human gingival fibroblasts (HGF-1). Despite the secretion of proliferation-promoting factors, DSCs caused no notable increase in the proliferation of human microvascular endothelial cells (HMEC-1). With regard to other aspects of the angiogenic cascade, DPSCs, SCAPs and HGF-1 significantly promoted endothelial migration in a transwell migration assay. DPSCs also had a pronounced effect on endothelial tubulogenesis, as was shown by an in vitro Matrigel™ assay. In the last part of this study, a chorioallantoic membrane assay demonstrated a sustained pro-angiogenic impact of DPSCs and SCAPs in an in vivo setting. Collectively, these data indicate a predominant pro-angiogenic influence of DPSCs and SCAPS in vitro and in vivo in comparison to FSCs, suggesting that both stem cell populations could potentially promote the vascularization of regenerated dental tissues." @default.
• W2034807185 created "2016-06-24" @default.
• W2034807185 creator A5018759326 @default.
• W2034807185 creator A5019355840 @default.
• W2034807185 creator A5025767182 @default.
• W2034807185 creator A5030237450 @default.
• W2034807185 creator A5034195360 @default.
• W2034807185 creator A5040028712 @default.
• W2034807185 creator A5050407222 @default.
• W2034807185 creator A5070903794 @default.
• W2034807185 date "2014-05-01" @default.
• W2034807185 modified "2023-09-29" @default.
• W2034807185 title "Pro-angiogenic impact of dental stem cells in vitro and in vivo" @default.
• W2034807185 cites W1495287184 @default.
• W2034807185 cites W1776910396 @default.
• W2034807185 cites W1967955370 @default.
• W2034807185 cites W1972255467 @default.
• W2034807185 cites W1977845985 @default.
• W2034807185 cites W1981708789 @default.
• W2034807185 cites W1982289725 @default.
• W2034807185 cites W1984592728 @default.
• W2034807185 cites W1989144555 @default.
• W2034807185 cites W1990062912 @default.
• W2034807185 cites W2004500783 @default.
• W2034807185 cites W2005452677 @default.
• W2034807185 cites W2005793412 @default.
• W2034807185 cites W2005943573 @default.
• W2034807185 cites W201727980 @default.
• W2034807185 cites W2023989480 @default.
• W2034807185 cites W2024579131 @default.
• W2034807185 cites W2025291066 @default.
• W2034807185 cites W2027012204 @default.
• W2034807185 cites W2027654288 @default.
• W2034807185 cites W2032801848 @default.
• W2034807185 cites W2034104304 @default.
• W2034807185 cites W2039218697 @default.
• W2034807185 cites W2043921440 @default.
• W2034807185 cites W2051662337 @default.
• W2034807185 cites W2052649805 @default.
• W2034807185 cites W2054095354 @default.
• W2034807185 cites W2055180992 @default.
• W2034807185 cites W2057925891 @default.
• W2034807185 cites W2073772438 @default.
• W2034807185 cites W2080151262 @default.
• W2034807185 cites W2080432848 @default.
• W2034807185 cites W2082040519 @default.
• W2034807185 cites W2084918030 @default.
• W2034807185 cites W2089823801 @default.
• W2034807185 cites W2090200028 @default.
• W2034807185 cites W2095132685 @default.
• W2034807185 cites W2098863391 @default.
• W2034807185 cites W2102021823 @default.
• W2034807185 cites W2102069687 @default.
• W2034807185 cites W2110418207 @default.
• W2034807185 cites W2112558234 @default.
• W2034807185 cites W2114429558 @default.
• W2034807185 cites W2116581961 @default.
• W2034807185 cites W2123982848 @default.
• W2034807185 cites W2126822734 @default.
• W2034807185 cites W2128313001 @default.
• W2034807185 cites W2130516299 @default.
• W2034807185 cites W2132054745 @default.
• W2034807185 cites W2137612350 @default.
• W2034807185 cites W2142639029 @default.
• W2034807185 cites W2145040826 @default.
• W2034807185 cites W2149709195 @default.
• W2034807185 cites W2154720360 @default.
• W2034807185 cites W2157010337 @default.
• W2034807185 cites W2158837806 @default.
• W2034807185 cites W2345735458 @default.
• W2034807185 doi "https://doi.org/10.1016/j.scr.2014.03.008" @default.
• W2034807185 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24747218" @default.
• W2034807185 hasPublicationYear "2014" @default.
• W2034807185 type Work @default.
• W2034807185 sameAs 2034807185 @default.
• W2034807185 citedByCount "96" @default.
• W2034807185 countsByYear W20348071852015 @default.
• W2034807185 countsByYear W20348071852016 @default.
• W2034807185 countsByYear W20348071852017 @default.
• W2034807185 countsByYear W20348071852018 @default.
• W2034807185 countsByYear W20348071852019 @default.
• W2034807185 countsByYear W20348071852020 @default.
• W2034807185 countsByYear W20348071852021 @default.
• W2034807185 countsByYear W20348071852022 @default.
• W2034807185 countsByYear W20348071852023 @default.
• W2034807185 crossrefType "journal-article" @default.
• W2034807185 hasAuthorship W2034807185A5018759326 @default.
• W2034807185 hasAuthorship W2034807185A5019355840 @default.
• W2034807185 hasAuthorship W2034807185A5025767182 @default.
• W2034807185 hasAuthorship W2034807185A5030237450 @default.
• W2034807185 hasAuthorship W2034807185A5034195360 @default.
• W2034807185 hasAuthorship W2034807185A5040028712 @default.
• W2034807185 hasAuthorship W2034807185A5050407222 @default.
• W2034807185 hasAuthorship W2034807185A5070903794 @default.
• W2034807185 hasBestOaLocation W20348071851 @default.
• W2034807185 hasConcept C170493617 @default.
• W2034807185 hasConcept C203014093 @default.
• W2034807185 hasConcept C2777400515 @default.

• next